Characteristics of Nosocomial Infections in Children Screened for SARS-CoV-2 Infection in China
| Autor: | Danyang Zhao, Peiqing Li, Qiang Wang, Jing Sun, Suyun Li, Jianjiang Yan, Haomei Yang, Jinxia Wu, Xian Cai, Weidong Zhu, Jing Huang, Guangming Liu, Jun Shen, Wencheng Ma, Qiaozhi Guo, Jiaming Luo, Xuan Shi, Weiqiang Xiao, Xin Sun, Daoju Jiang, Xiu-Lan Wen, Yan Hong, Jinai Lin, Huan Chen, Yongling Song |
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| Rok vydání: | 2020 |
| Předmět: |
Male
China medicine.medical_specialty Fever Isolation (health care) Disease 030204 cardiovascular system & hematology medicine.disease_cause Disease cluster Pediatrics Asymptomatic Medical Records 03 medical and health sciences 0302 clinical medicine Clinical Research Internal medicine Epidemiology medicine Humans Child Pandemics Retrospective Studies Coronavirus Cross Infection SARS-CoV-2 business.industry Medical record COVID-19 Multiphasic Screening Retrospective cohort study General Medicine Hospitals Patient Discharge Primary Prevention Hospitalization COVID-19 Nucleic Acid Testing Child Preschool 030220 oncology & carcinogenesis Female medicine.symptom business |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| DOI: | 10.12659/msm.928835 |
| Popis: | BACKGROUND This study summarizes the characteristics of children screened for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and reports the case of 1 child who was diagnosed with SARS-CoV-2 infection in Guangzhou Women and Children's Medical Center and the cases of his family members. MATERIAL AND METHODS The medical records of 159 children who were admitted to our hospital from January 23 to March 20, 2020, were retrospectively analyzed. Samples from pharyngeal or/and anal swabs were subjected to reverse-transcription polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 within 12 h of patient admission; a second RT-PCR test was done 24 h after the first test. RESULTS Of the 159 patients, 151 patients had epidemiological histories, 14 patients had cluster onset, and 8 patients had no epidemiological history but had symptoms similar to coronavirus disease 2019 (COVID-19). The most common symptom was fever (n=125), followed by respiratory and gastrointestinal symptoms. A 7-year-old boy in a cluster family from Wuhan was confirmed with asymptomatic SARS-CoV-2 infection with ground-glass opacity shadows on his lung computed tomography scan, and his swab RT-PCR test had not turned negative until day 19 of his hospitalization. In patients who did not test positive for SARS-CoV-2, influenza, respiratory syncytial virus, and adenovirus were observed. A total of 158 patients recovered, were discharged, and experienced no abnormalities during follow-up. CONCLUSIONS For SARS-CoV-2 nosocomial infections, taking a "standard prevention & contact isolation & droplet isolation & air isolation" strategy can prevent infection effectively. Children with clustered disease need close monitoring. |
| Databáze: | OpenAIRE |
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