Simultaneous Determination of Phenolic Compounds in Plasma by LC-ESI-MS/MS and Their Bioavailability after the Ingestion of Table Olives
| Autor: | Ivana Kundisová, Joana M. Planas, M. Emília Juan |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Chromatography Molecular Structure Phenol Salidroside Biological Availability General Chemistry Bioavailability Rats Sprague-Dawley Tyrosol Plasma chemistry.chemical_compound Verbascoside chemistry Pharmacokinetics Tandem Mass Spectrometry Polyphenol Fruit Olea Animals Hydroxytyrosol General Agricultural and Biological Sciences Luteolin Chromatography High Pressure Liquid |
| Zdroj: | Journal of Agricultural and Food Chemistry. 68:10213-10222 |
| ISSN: | 1520-5118 0021-8561 |
| Popis: | The role attributed to polyphenols on human health needs to be correlated with their plasmatic concentrations after food consumption. Then, a method based on liquid-liquid extraction followed by highly sensitive LC-ESI-MS/MS analysis was developed to determinate 16 phenolic compounds in plasma. Validation gave appropriate recovery, matrix effect (80%-120%), linear correlation (R2 > 0.995), precision ( |
| Databáze: | OpenAIRE |
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