Association of Serum Triiodothyronine With B-Type Natriuretic Peptide and Severe Left Ventricular Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction

Autor: Senthil Selvaraj, Irwin Klein, Sanjiv J. Shah, Nausheen Akhter, Sara Danzi, Robert O. Bonow
Rok vydání: 2012
Předmět:
Zdroj: The American Journal of Cardiology. 110:234-239
ISSN: 0002-9149
DOI: 10.1016/j.amjcard.2012.02.068
Popis: There are well-documented changes in thyroid hormone metabolism that accompany heart failure (HF). However, the frequency of thyroid hormone abnormalities in HF with preserved ejection fraction (HFpEF) is unknown, and no studies have investigated the association between triiodothyronine (T(3)) and markers of HF severity (B-type natriuretic peptide [BNP] and diastolic dysfunction [DD]) in HFpEF. In this study, 89 consecutive patients with HFpEF, defined as symptomatic HF with a left ventricular ejection fraction >50% and a left ventricular end-diastolic volume index
Databáze: OpenAIRE