Association of Serum Triiodothyronine With B-Type Natriuretic Peptide and Severe Left Ventricular Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction
Autor: | Senthil Selvaraj, Irwin Klein, Sanjiv J. Shah, Nausheen Akhter, Sara Danzi, Robert O. Bonow |
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Rok vydání: | 2012 |
Předmět: |
Male
medicine.medical_specialty medicine.drug_class Diastole Blood Pressure Hyperlipidemias Severity of Illness Index Article Ventricular Dysfunction Left Internal medicine Natriuretic Peptide Brain Diabetes Mellitus medicine Natriuretic peptide Humans Prospective Studies Aged Heart Failure Ejection fraction business.industry Age Factors Stroke Volume Stroke volume Middle Aged medicine.disease Pulse pressure Blood pressure Echocardiography Heart failure Multivariate Analysis Cardiology Triiodothyronine Female Cardiology and Cardiovascular Medicine Heart failure with preserved ejection fraction business |
Zdroj: | The American Journal of Cardiology. 110:234-239 |
ISSN: | 0002-9149 |
DOI: | 10.1016/j.amjcard.2012.02.068 |
Popis: | There are well-documented changes in thyroid hormone metabolism that accompany heart failure (HF). However, the frequency of thyroid hormone abnormalities in HF with preserved ejection fraction (HFpEF) is unknown, and no studies have investigated the association between triiodothyronine (T(3)) and markers of HF severity (B-type natriuretic peptide [BNP] and diastolic dysfunction [DD]) in HFpEF. In this study, 89 consecutive patients with HFpEF, defined as symptomatic HF with a left ventricular ejection fraction >50% and a left ventricular end-diastolic volume index |
Databáze: | OpenAIRE |
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