Effect of Renal Ischemia on Anaerobic CO2 Production by Dog Kidney in vitro
| Autor: | Julius J. Cohen, Howard M. Randall |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
medicine.medical_specialty
Kidney Cortex Ischemia Biology Kidney Malate dehydrogenase General Biochemistry Genetics and Molecular Biology Renal Circulation Dogs Oxygen Consumption Malate Dehydrogenase Internal medicine Cortex (anatomy) medicine Animals Citrate synthase Anaerobiosis Renal circulation Renal ischemia Anatomy Carbon Dioxide medicine.disease Disease Models Animal Endocrinology medicine.anatomical_structure biology.protein Anaerobic exercise |
| Zdroj: | Experimental Biology and Medicine. 125:947-953 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-125-32247 |
| Popis: | Summary1) Rates of anaerobic CO2 production by tissue obtained from dog kidneys with evidence of cortical ischemia have been compared with tissue from non-ischemic kidneys. Anaerobic CO2 production rate was consistent with the following coupled oxidation-reduction reaction: α-ketoglutarate + oxaloacetate + GDP + P1 → malate + succinate + CO2 + GTP. 2) Cortical washed homogenates from non-ischemic kidneys produced 14.6 ± 1.8 μmoles CO2/100 mg dry wt hr (M ± SE); cortical homogenates of ischemic kidneys yielded 6.0 ± 3.0 μmoles of CO2 (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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