Transanal Endoscopic Microsurgery (TEM) for rectal GI stromal tumor
| Autor: | Ahmer A. Karimuddin, S. Punnen, P. T. Phang, Manoj J. Raval, Carl J. Brown |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Transanal Endoscopic Microsurgery medicine.medical_specialty Gastrointestinal Stromal Tumors Colorectal cancer medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine medicine Positive Margins Humans Stromal tumor neoplasms Aged Retrospective Studies Aged 80 and over GiST Tumor size Rectal Neoplasms business.industry Imatinib General Medicine Middle Aged Microsurgery medicine.disease digestive system diseases 030220 oncology & carcinogenesis Anal verge Female 030211 gastroenterology & hepatology Surgery Radiology business medicine.drug |
| Zdroj: | The American Journal of Surgery. 221:183-186 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2020.07.013 |
| Popis: | Background Transanal endoscopic microsurgery (TEM) is effective in treating adenomas and select early rectal cancers. Our objective is to evaluate TEM in treating early rectal GISTs. Methods Patients were identified in a prospective database with pathology confirmed rectal GIST prior to TEM over 10 years. Demographic, pathologic, operative and follow-up data was analysed and presented with descriptive statistics. Results 7 cases of rectal GIST were treated with TEM with a follow-up time of 31 months (0–71). Median tumor distance from the anal verge was 4 cm (2.5–6) and median tumor size was 3 cm (2–5.7). Negative margins were achieved in 4/7 patients. Those with positive margins were treated with repeat TEM or imatinib. 1 patient had local recurrence successfully treated by TEM. Conclusions Overall, TEM is safe for locally excising GISTs. As rectal GISTs are rare, a multicenter registry may better elucidate outcomes with this treatment. |
| Databáze: | OpenAIRE |
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