18F-FDG PET/CT in the Management of Aortitis
| Autor: | Audrey Courtois, Jean-Olivier Defraigne, Natzi Sakalihasan, Philippe Delvenne, Samuel Bruls, Betty Nusgens, Roland Hustinx, Michel Moutschen |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Pathology Aortography 030204 cardiovascular system & hematology Multimodal Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 medicine.artery medicine Humans Radiology Nuclear Medicine and imaging Aorta Aortitis Aged Multimodal imaging medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Aortic wall Early Diagnosis Tomography x ray computed Positron emission tomography Positron-Emission Tomography Disease Progression cardiovascular system Female Fdg pet ct Radiology Tomography X-Ray Computed business |
| Zdroj: | Clinical Nuclear Medicine. 41:28-33 |
| ISSN: | 0363-9762 |
| DOI: | 10.1097/rlu.0000000000001016 |
| Popis: | Aortitis is a generic term defined as an inflammatory condition involving the aortic wall, of infectious or noninfectious origin. This inflammatory process may deteriorate the aortic wall, resulting in potentially life-threatening vascular complications. Therefore, it is important to establish a diagnosis as early as possible.During a 4-year period, 428 consecutive patients referred to our department for aortic diseases underwent FDG PET/CT examinations. Among these, 18 patients (4.2%) were suspected to have aortitis. All of them had an initial positive FDG PET/CT uptake occurring in the aorta and major branches as evaluated by visual analysis of images and assessed with the final diagnosis of aortitis. During follow-up, after surgery and/or upon immunosuppressive treatment, each of these patients underwent a second PET/CT that was compared with the initial evaluation. In all cases, normalization of FDG uptake was correlated with clinical improvement.Our study aimed to illustrate the potential clinical value of functional monitoring with PET/CT in the management of aortitis. FDG PET/CT constitutes a valuable imaging modality to establish an early diagnosis, monitor disease progression and treatment, and evaluate vascular complication and relapse. We highlight the importance of an early detection of inflammatory large-vessel pathology, which may represent a major threat. |
| Databáze: | OpenAIRE |
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