Diabetic peripheral neuropathy in ambulatory patients with type 2 diabetes in a general hospital in a middle income country: a cross-sectional study
| Autor: | Ray Ticse, Antonio Bernabe-Ortiz, J. Jaime Miranda, Miguel E. Pinto, Robert H. Gilman, Katherine A. Sacksteder, Germán Málaga, María de los Angeles Lazo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
age distribution Diabetic neuropathy Epidemiology Cross-sectional study lcsh:Medicine morbidity Type 2 diabetes Endocrinology ambulatory care Diabetic Neuropathies Risk Factors diabetic patient middle aged neurologic examination Peru onychomycosis Medicine and Health Sciences Ambulatory Care Prevalence middle income country Clinical Epidemiology nociception lcsh:Science hemoglobin A1c outpatient care Multidisciplinary purl.org/pe-repo/ocde/ford#3.02.18 [https] non insulin dependent diabetes mellitus adult article Middle Aged Semmes Weinstein monofilament test diabetic neuropathy Diabetic Foot achilles reflex Type 2 Diabetes aged diabetic retinopathy female risk factor Female vibration Research Article Adult insulin medicine.medical_specialty microalbuminuria foot malformation diabetic neuropathy symptom score complication oral antidiabetic agent Hospitals General Vibration perception socioeconomics blood Internal medicine Diabetes mellitus Diabetes Mellitus medicine cross-sectional study Humans controlled study human glycosylated hemoglobin Aged Hemoglobin A Glycosylated Diabetic Endocrinology Glycated Hemoglobin business.industry lcsh:R scoring system medicine.disease major clinical study Diabetic foot body mass Surgery general hospital Cross-Sectional Studies Peripheral neuropathy Diabetes Mellitus Type 2 Metabolic Disorders glycemic control lcsh:Q disease duration business Body mass index |
| Zdroj: | PLoS ONE, Vol 9, Iss 5, p e95403 (2014) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | AIM: We aimed to estimate the morbidity rate and associated factors for diabetic peripheral neuropathy (DPN) in a low-middle income country setting. METHODS: Cross-sectional study, data was gathered at Peru's Ministry of Health national specialized hospital for endocrinological conditions through standardized interviews, anthropometric measurements and blood tests for glycated haemoglobin (HbA1c). DPN was evaluated using two techniques: the Semmes-Weinstein monofilament test and the diabetic neuropathy symptom score. Overall prevalence and 95% confidence intervals (95% CI) were calculated. Potential factors related to DPN explored included body mass index, years with disease (/=10 years), glycaemic control (HbA1c /=7%), microalbuminuria, retinopathy, and current pharmacological treatment. Multivariable analysis was performed using Poisson analysis to calculate prevalence ratios. RESULTS: DPN was observed in 73/129 (56.6%) patients. In multivariable analysis adjusted by age and sex, the prevalence ratio of neuropathy was 1.4 times higher (95% CI 1.07-1.88) in patients who took insulin plus metformin compared to patients who used one treatment alone, and 1.4 higher (95% CI 1.02-1.93) in patients with >/=10 years of disease compared to those with a shorter duration of disease. Also we found some characteristics in foot evaluation associated to neuropathy such as deformities (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|