Clinical implementation of dynamic multileaf collimation for compensated bladder treatments
| Autor: | John P Logue, Judith H. L. Mott, Geoffrey J. Budgell, Alan R. Hounsell |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Radiation
Radiation Dosage Sensitivity and Specificity Sampling Studies Collimated light Imaging phantom Linear particle accelerator Radiotherapy High-Energy Humans Medicine Radiology Nuclear Medicine and imaging Radiation Injuries Test site Phantoms Imaging business.industry Radiotherapy Planning Computer-Assisted Carcinoma Dose-Response Relationship Radiation Hematology Prognosis Intensity (physics) Multileaf collimator Treatment Outcome Urinary Bladder Neoplasms Oncology Intensity modulated radiotherapy Nuclear medicine business |
| Zdroj: | Radiotherapy and Oncology. 59:31-38 |
| ISSN: | 0167-8140 |
| DOI: | 10.1016/s0167-8140(00)00281-4 |
| Popis: | Background and purpose : To describe the clinical implementation of dynamic multileaf collimation (DMLC). Custom compensated four-field treatments of carcinoma of the bladder have been used as a simple test site for the introduction of intensity modulated radiotherapy. Materials and methods : Compensating intensity modulations are calculated from computed tomography (CT) data, accounting for scattered, as well as primary radiation. Modulations are converted to multileaf collimator (MLC) leaf and jaw settings for dynamic delivery on a linear accelerator. A full dose calculation is carried out, accounting for dynamic leaf and jaw motion and transmission through these components. Before treatment, a test run of the delivery is performed and an absolute dose measurement made in a water or solid water phantom. Treatments are verified by in vivo diode measurements and real-time electronic portal imaging. Results : Seven patients have been treated using DMLC. The technique improves dose homogeneity within the target volume, reducing high dose areas and compensating for loss of scatter at the beam edge. A typical total treatment time is 20 min. Conclusions : Compensated bladder treatments have proven an effective test site for DMLC in an extremely busy clinic. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect