Childhood Pulmonary Blastoma: A Pleuropulmonary Variant of the Adult-Type Pulmonary Blastoma
| Autor: | Malcolm Emms, R. O. C. Kaschula, Marta C. Cohen |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lung Neoplasms alpha 1-Antichymotrypsin Mesenchyme Malignant Mesenchymoma Epithelium Desmin Pathology and Forensic Medicine Mesoderm Mesenchymoma Humans Vimentin Medicine Rhabdomyosarcoma Lung Myoglobin business.industry Cartilage S100 Proteins Teratoma medicine.disease Immunohistochemistry Carcinoembryonic Antigen Pulmonary Blastoma Microscopy Electron medicine.anatomical_structure Child Preschool Phosphopyruvate Hydratase alpha 1-Antitrypsin Pediatrics Perinatology and Child Health Keratins Female business Blastema |
| Zdroj: | Pediatric Pathology. 11:737-749 |
| ISSN: | 0277-0938 |
| DOI: | 10.3109/15513819109065469 |
| Popis: | Two fatal childhood cases of the rare pulmonary blastoma are reported. One was associated with a congenital cystic adenomatoid malformation. Both neoplasms extended to involve visceral pleura and were entirely composed of blastemal and mesenchymal elements without recognizable neoplastic epithelial components. The mesenchymal component in both instances consisted of malignant rhabdomyoblasts, undifferentiated mesenchyme, and differentiated, apparently benign, cartilage. Review of the literature suggests that these features may be specific for the childhood forms of pulmonary blastoma. It is further suggested that pulmonary blastoma, malignant mesenchymoma of the lung, and primary pulmonary rhabdomyosarcoma may have a common pathogenetic origin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|