Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report
Autor: | Si-ying Song, Zhong-ao Wang, Yu-chuan Ding, Xun-ming Ji, Ran Meng |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Intracerebral hemorrhage
medicine.medical_specialty Cerebral infarction business.industry cyclosporine-A medicine.disease lcsh:RC346-429 Brain ischemia Venous thrombosis Neurology systematic review Internal medicine medicine Cardiology case report Neurology (clinical) Cerebral venous sinus thrombosis Aplastic anemia business Stroke cerebral venous sinus thrombosis Thrombotic complication lcsh:Neurology. Diseases of the nervous system cerebral arterial infarction |
Zdroj: | Frontiers in Neurology, Vol 11 (2021) Frontiers in Neurology |
ISSN: | 1664-2295 |
Popis: | This study reported two cases of intracranial thrombotic events of aplastic anemia (AA) under therapy with cyclosporine-A (CsA) and reviewed both drug-induced cerebral venous thrombosis (CVT) and CsA-related thrombotic events systematically. We searched PubMed Central (PMC) and EMBASE up to Sep 2019 for publications on drug-induced CVT and Cs-A-induced thrombotic events. Medical subject headings and Emtree headings were used with the following keywords: “cyclosporine-A” and “cerebral venous thrombosis OR cerebral vein thrombosis” and “stroke OR Brain Ischemia OR Brain Infarction OR cerebral infarction OR intracerebral hemorrhage OR intracranial hemorrhage.” We found that CsA might be a significant risk factor in inducing not only CVT but also cerebral arterial thrombosis in patients with AA. |
Databáze: | OpenAIRE |
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