Static mode microfluidic cantilevers for detection of waterborne pathogens
| Autor: | Wenmiao Shu, Helen Bridle, Farid Amalou, Duncan Paul Hand, Despoina Gavriilidou, Wenxing Wang |
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| Rok vydání: | 2016 |
| Předmět: |
Analyte
Fabrication Materials science Cantilever 010401 analytical chemistry Microfluidics Metals and Alloys Nanotechnology 02 engineering and technology Quartz crystal microbalance 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials TA164 Microfluidic channel Static mode Electrical and Electronic Engineering 0210 nano-technology Instrumentation Biosensor |
| Zdroj: | Sensors and Actuators A: Physical. 247:144-149 |
| ISSN: | 0924-4247 |
| DOI: | 10.1016/j.sna.2016.05.011 |
| Popis: | This paper reports on the first demonstration of polymeric microfluidic cantilever sensors. Microcantilever sensors, magnetic beads, and microfluidic technology have been combined to create a polymer based biosensor. Using cheap materials like polyimide, a simple fabrication method has been developed to produce cantilevers with an embedded microfluidic channel. The advantage of this approach is that the addition of a microfluidic channel enables the analysis of smaller volumes and increases the capture efficiency in applications detecting rare analytes. As a proof of principle the system has been applied for the detection of the waterborne protozoan parasite Cryptosporidium, achieving sensitivity comparable to QCM, whereas a previous set-up without the microfluidic channel was unable to detect the parasite. |
| Databáze: | OpenAIRE |
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