Prefrontal contributions to initiation, suppression and strategy: A neuropsychological study of focal frontal patients
| Autor: | Robinson Gail, Bozzali Marco, Biggs Vivien, Walker David, Shallice Tim, Cipolotti Lisa |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Neural correlates of consciousness
medicine.medical_specialty Frontal cortex Neuropsychology Audiology behavioral disciplines and activities Sentence completion tests Behavioral Neuroscience Psychiatry and Mental health Hayling test Neuropsychology and Physiological Psychology Neurology Frontal lobe medicine In patient Psychology Biological Psychiatry Cognitive psychology |
| Zdroj: | University of Queensland |
| ISSN: | 1662-5161 |
| DOI: | 10.3389/conf.fnhum.2015.217.00361 |
| Popis: | Initiation and suppression deficits are documented in patients with frontal lesions although this has typically been with different tasks that are hard to compare. The Hayling Sentence Completion Test (Burgess & Shallice, 1997) was designed to tap initiation, suppression and strategy use within the same sentence completion task. There are few studies specifically investigating the neural correlates of initiation and suppression using the same task in frontal patients. We investigated initiation, suppression and strategy use on the Hayling Test in 40 frontal patients, 30 posterior patients and 40 matched healthy controls. Lesions were analysed with a finer-grained frontal localisation method (Right/Left Lateral, Medial) and traditional methods (i.e., anterior/posterior). We analysed the standard clinical measures (Initiation RT, Suppression RT, Suppression Errors and Overall Score), composite error scores and strategic responses. The results showed that all four Hayling Test clinical measures were sensitive to frontal lesions; however, only Suppression Errors and the Overall measure were specific to frontal lobe damage. All frontal patients produced blatant suppression failures but there was a specific Right Lateral frontal effect for producing subtly incorrect responses. In addition, Right Lateral patients produced fewer correct strategic responses and incurred longer response times in doing so. These findings suggest that the right lateral frontal cortex plays a role in suppression and strategic processes. |
| Databáze: | OpenAIRE |
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