Post-pericardiotomy syndrome: insights into neglected postoperative issues
| Autor: | Francesco Maranta, Ottavio Alfieri, Domenico Cianflone, Massimo Imazio, Lorenzo Cianfanelli, Rocco Grippo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry POST PERICARDIOTOMY SYNDROME Retrospective cohort study General Medicine medicine.disease Pericardial effusion Cardiac surgery Clinical Practice Pericarditis Pericardiectomy Epidemiology Postpericardiotomy Syndrome medicine Humans Surgery Prospective Studies Cardiac Surgical Procedures Cardiology and Cardiovascular Medicine Intensive care medicine business Complication Retrospective Studies |
| Zdroj: | European Journal of Cardio-Thoracic Surgery. 61:505-514 |
| ISSN: | 1873-734X 1010-7940 |
| DOI: | 10.1093/ejcts/ezab449 |
| Popis: | Abstract OBJECTIVESPericardial effusion is a common complication after cardiac surgery, both isolated and in post-pericardiotomy syndrome (PPS), a condition in which pleuropericardial damage triggers both a local and a systemic inflammatory/immune response. The goal of this review was to present a complete picture of PPS and pericardial complications after cardiac surgery, highlighting available evidence and gaps in knowledge.METHODSA literature review was performed that included relevant prospective and retrospective studies on the subject.RESULTSPPS occurs frequently and is associated with elevated morbidity and significantly increased hospital stays and costs. Nevertheless, PPS is often underestimated in clinical practice, and knowledge of its pathogenesis and epidemiology is limited. Several anti-inflammatory drugs have been investigated for treatment but with conflicting evidence. Colchicine demonstrated encouraging results for prevention.CONCLUSIONSWider adoption of standardized diagnostic criteria to correctly define PPS and start early treatment is needed. Larger studies are necessary to better identify high-risk patients who might benefit from preventive strategies. |
| Databáze: | OpenAIRE |
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