Correlates of uptake of optimal doses of sulfadoxine-pyrimethamine for prevention of malaria during pregnancy in East-Central Uganda

Autor: Kikaire Bernard, Twesigye Rogers, Mbonye Kayitale Martin, Kirwana B. Venantius, Asiimwe Godfrey, Byonanebye M. Dathan, Ndugga Patricia, Baleeta Keith, Kadengye T. Damazo, Kabagenyi Allen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
medicine.medical_specialty
Multivariate analysis
lcsh:Arctic medicine. Tropical medicine
Adolescent
lcsh:RC955-962
030231 tropical medicine
lcsh:Infectious and parasitic diseases
Antimalarials
Young Adult
03 medical and health sciences
0302 clinical medicine
Pregnancy
Sulfadoxine
parasitic diseases
medicine
Humans
Uganda
lcsh:RC109-216
030212 general & internal medicine
Adverse effect
Multinomial logistic regression
Dose-Response Relationship
Drug
business.industry
Research
Public health
Intermittent preventive treatment during pregnancy
Demographic and health survey
Middle Aged
Patient Acceptance of Health Care
medicine.disease
Sulfadoxine/pyrimethamine
Malaria
Drug Combinations
Pyrimethamine
Infectious Diseases
Socioeconomic Factors
Female
Parasitology
business
Live birth
Demography
medicine.drug
Zdroj: Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Malaria Journal
ISSN: 1475-2875
DOI: 10.1186/s12936-020-03230-8
Popis: Background In 2012, the World Health Organization recommended that pregnant women in malaria-endemic countries complete at least three (optimal) doses of intermittent preventive treatment (IPTp) using sulfadoxine-pyrimethamine (SP) to prevent malaria and related adverse events during pregnancy. Uganda adopted this recommendation, but uptake remains low in East-Central and information to explain this low uptake remains scanty. This analysis determined correlates of uptake of optimal doses of IPTp-SP in East-Central Uganda. Methods This was a secondary analysis of the 2016 Uganda Demographic Health Survey data on 579 women (15–49 years) who attended at least one antenatal care (ANC) visit and had a live birth within 2 years preceding the survey. Uptake of IPTp-SP was defined as optimal if a woman received at least three doses; partial if they received 1–2 doses or none if they received no dose. Multivariate analysis using multinomial logistic regression was used to determine correlates of IPTp-SP uptake. Results Overall, 22.3% of women received optimal doses of IPTp-SP, 48.2% partial and 29.5% none. Attending ANC at a lower-level health centre relative to a hospital was associated with reduced likelihood of receiving optimal doses of IPTp-SP. Belonging to other religious faiths relative to Catholic, belonging to a household in the middle relative to poorest wealth index, and age 30 and above years relative to 25–29 years were associated with higher likelihood of receiving optimal doses of IPTp-SP. Conclusions In East-Central Uganda, uptake of optimal doses of IPTp-SP is very low. Improving institutional delivery and household wealth, involving religious leaders in programmes to improve uptake of IPTp-SP, and strengthening IPTp-SP activities at lower level health centers may improve uptake of IPTp-SP in the East-Central Uganda.
Databáze: OpenAIRE
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