Mitral annular peak systolic and diastolic velocities are characteristic of healthy hearts: A Doppler tissue imaging study
| Autor: | Randell C. Thomas, Timothy F. Simpson, Nelson B. Schiller, Jeffrey M. Tyler, Qizhi Fang, Dwight Bibby |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Cardiac function curve medicine.medical_specialty Composite score Systole Diastole 030204 cardiovascular system & hematology Sensitivity and Specificity Severity of Illness Index Ventricular Function Left 030218 nuclear medicine & medical imaging Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Reference Values Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging Doppler tissue imaging Univariate analysis business.industry Area under the curve Reproducibility of Results Ultrasonography Doppler Middle Aged Cohort Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Echocardiography. 36:433-438 |
| ISSN: | 0742-2822 |
| DOI: | 10.1111/echo.14247 |
| Popis: | INTRODUCTION Although systolic and diastolic dysfunction must coexist, they are most often considered in isolation. Therefore, a simple and reproducible quantitative measurement that integrates systolic and diastolic function is desirable. We hypothesize that the absolute sum of lateral mitral annular systolic and early diastolic peak velocities is predictive of overall cardiac function. METHODS In this study, lateral mitral annular systolic (S') and early diastolic (E') peak velocities were measured in healthy subjects and compared against subjects with progressive degrees of systolic and diastolic dysfunction. RESULTS A total of 149 subjects (56% male, mean age 48 years) were enrolled and stratified according to global left ventricular function: 76 normal, 40 mild-moderate dysfunction, and 33 moderate-severe dysfunction. Adjusting for baseline differences including age, univariate analysis showed mean S' + E' values were significantly different between subjects with normal, mild-moderate, and moderate-severe global left ventricular function (27, 17, 13 cm/s; P |
| Databáze: | OpenAIRE |
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