Comparison of Total Antioxidant Capacity (TAC) in the Multibacillary (MB) Type of Leprosy Patients Before and After 3 Months of MDT-MB WHO Therapy
| Autor: | Sri Vitayani Muchtar, Idham Jaya Ganda, Dinie Ramdhani Kusuma, Sitti Nur Rahmah, Khairuddin Djawad, Agussalim Bukhari, Safruddin Amin |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Antioxidant biology business.industry medicine.medical_treatment lcsh:R lcsh:Medicine Dapsone biology.organism_classification medicine.disease Leprosy MB Gastroenterology Total antioxidant capacity (TAC) Clofazimine Pharmacotherapy Internal medicine medicine Leprosy business Prospective cohort study Mycobacterium leprae Rifampicin MDT-MB WHO medicine.drug |
| Zdroj: | International Journal of Medical Reviews and Case Reports, Vol 2, Iss 4, Pp 136-142 (2018) |
| ISSN: | 2534-9821 |
| Popis: | Leprosy is chronic infectious disease caused by the intracellular parasitic pathogen Mycobacterium Leprae involves accumulation of highly reactive oxygen species (ROS) production and decreased levels of antioxidant in affected individuals. The present treatment method available for leprosy is MDT (Multi Drug Therapy) from WHO (World Health Organization) involves combination of Rifampicin, Dapsone and Clofazimine. In this cohort prospective study, we have investigated total antioxidant capacity (TAC) in 16 multibacillary leprosy patients before and after 3 months of MDT-MB WHO. In this study, we present that mean values of total antioxidant capacity (TAC) after 3 months of MDT-MB WHO were higher than before treated. From the sample groups in this study, we also found an decrease TAC levels in higher bacterial index after 3 months of MDT-MB WHO, this further increases significantly (p |
| Databáze: | OpenAIRE |
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