Physical Activity and Symptoms in Pulmonary Arterial Hypertension

Autor: Haochang Shou, Christine Archer-Chicko, Harold I. Palevsky, Diane Pinder, Marilyn S. Sommers, Anjali Vaidya, Steven M. Kawut, Danielle Dubow, Lea Ann Matura, K. Akaya Smith, Jason S. Fritz
Rok vydání: 2016
Předmět:
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Multivariate analysis
Intraclass correlation
Hypertension
Pulmonary
Psychological intervention
Physical activity
Motor Activity
030204 cardiovascular system & hematology
Critical Care and Intensive Care Medicine
Metabolic equivalent
Original Research: Pulmonary Vascular Disease
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Accelerometry
Activities of Daily Living
Humans
Medicine
Prospective Studies
Cambridge Pulmonary Hypertension Outcome Review
Prospective cohort study
business.industry
Multidimensional Fatigue Inventory
Middle Aged
Mental Fatigue
United States
030228 respiratory system
Exercise Test
Physical Endurance
Physical therapy
Female
Self Report
Sedentary Behavior
Cardiology and Cardiovascular Medicine
business
Zdroj: Chest. 150:46-56
ISSN: 0012-3692
DOI: 10.1016/j.chest.2016.02.633
Popis: Background Fatigue is a common symptom in patients with pulmonary arterial hypertension (PAH); however, the impact of fatigue on daily physical activity in PAH is unknown. Accelerometry is a validated measure for assessing physical activity. We hypothesized that patients with PAH reporting higher levels of fatigue would have lower daily physical activity measured by accelerometry. Methods We performed a prospective cohort study of 15 women with PAH. On day 1, subjects completed the Multidimensional Fatigue Inventory (MFI), the United States Cambridge Pulmonary Hypertension Outcome Review (US CAMPHOR), and a 6-min walk test. Subjects wore the accelerometer on their dominant hip and completed an activity diary for 7 days. On day 15, subjects repeated the MFI and the US CAMPHOR, and then wore the accelerometer and completed an activity diary for an additional 7 days. All multivariate analyses were adjusted for age, BMI, and PAH type. Results The mean age was 50.5 years, and 53% had idiopathic or heritable PAH. During the 2 weeks, subjects were mostly sedentary (85% of the time), although 10% of their time was spent performing low-level activity. Lower average daily counts were associated with worse self-reported energy levels, whereas less day-to-day physical activity variability was associated with more self-reported mental fatigue, physical fatigue, and total activity. Higher percentage of activity bouts was also associated with worse energy. Conclusions Women with PAH may spend most of their time being sedentary, and lower self-reported energy levels are associated with less daily activity. Interventions to improve symptoms such as fatigue may also increase physical activity levels in PAH.
Databáze: OpenAIRE
Externí odkaz: