Early Detection of Neurophysiological Abnormalities in Infection by Human Immunodeficiency Virus
| Autor: | Cristina Aznar-Bueno, Juan Antonio Amiguet, Francisco Abad-Alegría |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Nervous system Pathology medicine.medical_specialty Neural Conduction HIV Infections Sural nerve Somatosensory system Nerve conduction velocity HIV Seronegativity Electroneuronography medicine Humans Evoked potential Evoked Potentials Motor Neurons business.industry Peripheral Nervous System Diseases Middle Aged Electrophysiology medicine.anatomical_structure Somatosensory evoked potential Case-Control Studies Immunology Disease Progression HIV-1 Female Neurology (clinical) Nervous System Diseases Immunocompetence business |
| Zdroj: | Clinical Electroencephalography. 31:116-121 |
| ISSN: | 0009-9155 |
| DOI: | 10.1177/155005940003100211 |
| Popis: | The human immunodeficiency virus causes serious, progressive and irreversible deterioration of the immunocompetence system and of the nervous system, so neurological pathology in infected patients is frequent (30-40%), affecting both the central and the peripheral nervous systems. There are different clinical and laboratory indicators of bad prognosis, considering the important neurotropism of the virus. This study attempts to evaluate which neurophysiological parameters are altered during the initial phases of infection by HIV. A total of 46 individuals were studied, 30 seronegative and 16 seropositive in stage A of the CDC-93 classification. Motor and sensory conduction studies were carried out on all of them on the upper and lower extremities, as well as visual, somatosensory and auditory evoked potentials and endogenous potentials, mainly P300. The analysis of the neurophysiological parameters evaluated in our series, showed alterations of the conduction velocity of the sural nerve, latency of N1 of the SSEP of median and posterior tibial nerves and P300 in the initial phases of the infection even in the absence of clinical symptomatology. |
| Databáze: | OpenAIRE |
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