A seroprevalence study of poliovirus antibody against a collection of recombinant and non-recombinant poliovirus vaccine strains in the population of southern Greece

Autor: Stamatina Levidiotou-Stefanou, P. Kioussi, Z. Kyriakopoulou, M. Megalou, I. G. A. Ruether, E. Plakokefalos, Panayotis Markoulatos, Vaia Pliaka, Anastassia Pratti
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Poliovirus Vaccines/administration & dosage/*immunology
Booster dose
medicine.disease_cause
Antibodies
Viral

Seroepidemiologic Studies
Antibodies
Viral/*blood

Child
Poliovirus/*immunology
education.field_of_study
Vaccines
Synthetic

Greece
Poliovirus
Vaccination
General Medicine
Vaccines
Attenuated/administration & dosage/*immunology

Poliomyelitis
Poliovirus Vaccines
Infectious Diseases
Child
Preschool

Microbiology (medical)
Adult
Poliomyelitis/epidemiology/immunology/prevention & control
Adolescent
Population
Immunization
Secondary

Greece/epidemiology
Vaccines
Synthetic/administration & dosage/immunology

Vaccines
Attenuated

complex mixtures
Microbiology
Herd immunity
OPV derivatives
Poliovirus Vaccine
Oral/administration & dosage/*immunology

Neutralization Tests
medicine
Seroprevalence
Humans
education
Immunization Schedule
business.industry
Infant
medicine.disease
Virology
immunity
Poliovirus Vaccine
Oral

Enterovirus
Polioviruses
business
Popis: In this study, the serological status of the southern Greek population in the 1-10-year, 11-20-year, 21-30-year and 31-40-year age groups with regard to Sabin vaccine strains and a collection of 15 recombinant and four non-recombinant poliovirus vaccine strains was determined. For all three poliovirus types, the highest neutralization test (NT) titres were observed in the 1-10- year age group, indicating a good response to vaccination. In general, the serological status of the population of southern Greece with regard to poliovirus is better for types 1 and 2 than for type 3. The presence of the lowest NT titre in the 21- 30-year age group against poliovirus type 3 suggests the need for a booster dose of monovalent Sabin3 vaccine to ensure personal and herd immunity. Clin Microbiol Infect
Databáze: OpenAIRE