Deep Tissue Penetration of Bottle-Brush Polymers via Cell Capture Evasion and Fast Diffusion

Autor: Jean-Michel Rabanel, Marziye Mirbagheri, Mateusz Olszewski, Guojun Xie, Marine Le Goas, Pierre-Luc Latreille, Hermine Counil, Vincent Hervé, Rummenigge Oliveira Silva, Charlotte Zaouter, Vahid Adibnia, Mariana Acevedo, Marc J. Servant, Vincent A. Martinez, Shunmoogum A. Patten, Krzysztof Matyjaszewski, Charles Ramassamy, Xavier Banquy
Rok vydání: 2022
Předmět:
Zdroj: ACS nano.
ISSN: 1936-086X
Popis: Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply penetrating into dense tissues of the CNS could potentially transform the management of neurological diseases. In the present study, we investigated the interaction of bottle-brush (BB) polymers with different biological barriers
Databáze: OpenAIRE