Quality of life among female patients with systemic lupus erythematosus in remission
| Autor: | Parasar Ghosh, Rudra Prosad Goswami, Geetabali Sircar, Alakendu Ghosh, Rudrani Chatterjee |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Health Status Immunology Population India Disease Young Adult Sex Factors Rheumatology Quality of life Interquartile range Internal medicine Prevalence medicine Humans Lupus Erythematosus Systemic Immunology and Allergy Prospective Studies education Fatigue Depression (differential diagnoses) education.field_of_study Depression business.industry Remission Induction Complete remission Middle Aged Confidence interval Affect Mental Health Treatment Outcome Case-Control Studies Quality of Life Female business Immunosuppressive Agents |
| Zdroj: | Rheumatology International. 39:1351-1358 |
| ISSN: | 1437-160X 0172-8172 |
| DOI: | 10.1007/s00296-019-04329-1 |
| Popis: | The objective is to assess quality-of-life (QoL) parameters among Indian female systemic lupus erythematosus (SLE) patients with durable remission. Indian female SLE patients in remission determined by the European consensus criteria and age-matched female control participants were included in the study. All included participants underwent measurements of QoL [Medical Outcomes Study Short-Form-12 (SF12)], Fatigue Severity Scale, and structured interview with a clinical psychologist. The population comprised of 126 female SLE patients [median age: 27.5 years [interquartile range (IQR): 11]; median disease duration: 36 months (IQR 26)] and 110 female controls [median age 30 years (IQR 9)]. Clinical remission was seen in 65.9% (83/126) and complete remission in 34.1% (43/126). Significant fatigue was present in 18.3% (23/126). Both SF-12 physical component summary (PCS) and mental component summary (MCS) were similar between SLE patients and controls [median PCS: 50.3 (IQR: 16.2) vs. 48.6 (IQR: 11.6); median MCS: 57.2 (IQR: 4.8) vs. 57.9 (IQR: 7.6)]. In generalised linear modelling, PCS was associated with fatigue [odd’s ratio (OR) 0.012, 95% confidence interval (CI) 0.006–0.025, p |
| Databáze: | OpenAIRE |
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