Successful recovery of MERS CoV pneumonia in a patient with acquired immunodeficiency syndrome: A case report

Autor:	Raed Simhairi, Abdulwahab AlZahrani, Sarah Shalhoub, Adnan Mushtaq
Rok vydání:	2015
Předmět:	Male Pediatrics medicine.medical_specialty Middle East respiratory syndrome coronavirus viruses Pneumonia Viral Human immunodeficiency virus (HIV) TMP/SX trimethoprim/sulfamethoxazole Biology medicine.disease_cause PJP pneumocystis jirovecii pneumonia Antiviral Agents Article RT-PCR reverse transcription polymerase chain reaction Acquired immunodeficiency syndrome (AIDS) MERS Antiretroviral Therapy Highly Active Virology medicine Immunodeficiency Humans In patient Acquired Immunodeficiency Syndrome MERS CoV Middle East Respiratory Syndrome Coronavirus ELISA Enzyme Linked Immunosorbent Assay Pneumocystis jirovecii Pneumonia HIV virus diseases Cytomegalovirus CMV cytomegalovirus Pneumonia biochemical phenomena metabolism and nutrition Middle Aged medicine.disease CT computed tomography respiratory tract diseases Treatment Outcome Infectious Diseases Middle East Respiratory Syndrome Coronavirus Radiography Thoracic Steroids Coronavirus Infections HIV Human Immunodeficiency Virus
Zdroj:	Journal of Clinical Virology
ISSN:	1386-6532
DOI:	10.1016/j.jcv.2014.11.030
Popis:	Highlights • MERS coronavirus causes severe morbidity and mortality. • The effect of HIV positivity on the severity of MERS CoV is unknown. • Shedding of MERS CoV in an HIV patient continued for 38 days. • Interferon α2a followed by interferon β1a with ribavirin were used for treatment. • The effect of interferon α2a and β1a on treating MERS CoV remains to be elucidated. Middle East Respiratory Syndrome Coronavirus (MERS CoV) may cause severe pneumonia with significant morbidity and mortality, particularly in patients with multiple comorbid condition. MERS CoV pneumonia has not been previously reported in patients with Human Immunodeficiency Virus (HIV). Herein, we report a case of MERS CoV pneumonia with a successful outcome in a patient recently diagnosed with HIV.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9269d2a5dd8da683c0062bd8a5acea95 https://doi.org/10.1016/j.jcv.2014.11.030 Zobrazit plný text záznamu Full Text from ScienceDirect