Systematic analysis of post-treatment soft-tissue edema and seroma on MRI in 177 sarcoma patients
| Autor: | Sam Sedaghat, Maya Sedaghat, Frederick Schmitz, Jens Meschede |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Soft Tissue Neoplasms Severity of Illness Index 030218 nuclear medicine & medical imaging 03 medical and health sciences Postoperative Complications 0302 clinical medicine Risk Factors Germany Edema medicine Humans Aged Radiotherapy business.industry Muscles Soft tissue Sarcoma Middle Aged medicine.disease Magnetic Resonance Imaging Primary tumor Radiation therapy Seroma medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Female Surgery Radiology medicine.symptom Post treatment business Subcutaneous tissue |
| Zdroj: | Surgical Oncology. 35:218-223 |
| ISSN: | 0960-7404 |
| DOI: | 10.1016/j.suronc.2020.08.023 |
| Popis: | Purpose To assess post-treatment subcutaneous edema, muscle edema, and seroma in MRI after soft-tissue sarcoma (STS) resection with regard to muscle involvement of STS and therapy. Methods In all, 177 patients were included and received 1.5-T MRI follow-up examinations after treatment. Post-treatment changes were classified according to type of therapy (therapy 1-surgery; therapy 2-surgery with radiation therapy) and primary tumor localization in soft tissue (localization 1, subcutaneous tissue; localization 2, muscle involvement). Subcutaneous and muscle edema were divided into three grades: grade 0, absence of edema; grade 1, low-to-moderate edema; and grade 2, high-grade edema. Results The mean age of the patients was 55.7 ± 18.2 years and the mean volume of the resected primary STS was 321.5 cm3. After therapy 1 of a sarcoma in localization 1, patients significantly more often showed low-grade subcutaneous tissue edema and an absence of muscle edema (p Conclusion High-grade postoperative subcutaneous and muscle edema are significantly associated with muscle involvement of primary STS both in patients with and without radiation therapy. The risk for seroma is significantly higher after surgery with additional radiation therapy than after surgery alone. |
| Databáze: | OpenAIRE |
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