Comparison of 2-year clinical outcomes between diabetic versus nondiabetic patients with acute myocardial infarction after 1-month stabilization
| Autor: | Seok Kyu Oh, Dong-Ju Choi, Hyeon Cheol Gwon, Wooyeong Jang, Donghoon Choi, Ki-Bum Won, Jang Ho Bae, Seung Ho Hur, Joon Hong Kim, In-Cheol Kim, Kyoo Rok Han, Hyo-Soo Kim, Kyung-Kuk Hwang, Kee Sik Kim, Seung-Woon Rha, Kyung Tae Jung, Rak Kyeong Choi, So-Yeon Choi, Jang Whan Bae, Hun Sik Park, Do Sun Lim, Jae-Hwan Lee, Eun-Seok Shin, Jong Seon Park, Jung Han Yoon, Young Keun Ahn |
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| Rok vydání: | 2016 |
| Předmět: |
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medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Observational Study acute myocardial infarction Kaplan-Meier Estimate 030204 cardiovascular system & hematology Risk Assessment 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Risk Factors Cause of Death Internal medicine Republic of Korea Diabetes Mellitus medicine Humans Prospective Studies Registries cardiovascular diseases 030212 general & internal medicine Myocardial infarction Propensity Score Prospective cohort study major adverse cardiac events Survival rate Cause of death Ejection fraction business.industry Incidence Percutaneous coronary intervention General Medicine Middle Aged Prognosis medicine.disease Survival Rate Treatment Outcome ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Cardiology Female business Mace Follow-Up Studies Research Article Kidney disease |
| Zdroj: | Medicine |
| ISSN: | 0025-7974 |
| DOI: | 10.1097/md.0000000000003882 |
| Popis: | Supplemental Digital Content is available in the text This study assessed the 2-year clinical outcomes of patients with diabetes mellitus (DM) after acute myocardial infarction (AMI) in a cohort of the DIAMOND (DIabetic Acute Myocardial infarctiON Disease) registry. Clinical outcomes were compared between 1088 diabetic AMI patients in the DIAMOND registry after stabilization of MI and 1088 nondiabetic AMI patients from the KORMI (Korean AMI) registry after 1 : 1 propensity score matching using traditional cardiovascular risk factors. Stabilized patients were defined as patients who did not have any clinical events within 1 month after AMI. Primary outcomes were the 2-year rate of major adverse cardiac events (MACEs), a composite of all-cause death, recurrent MI (re-MI), and target vessel revascularization (TVR). Matched comparisons revealed that diabetic patients exhibited significantly lower left ventricular ejection fraction (LVEF) and estimated glomerular filtration rate and smaller stent size. Diabetic patients exhibited significantly higher 2-year rates of MACE (8.0% vs 3.7%), all-cause death (3.9% vs 1.4%), re-MI (2.8% vs 1.2%), and TVR (3.5% vs 1.3%) than nondiabetic patients (all P |
| Databáze: | OpenAIRE |
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