Myocardial Function Following Repair of Anomalous Origin of Left Coronary Artery from the Pulmonary Artery in Children
| Autor: | Martin Kostolny, Shreesha Maiya, Jan Marek, Nagarajan Muthialu, Mun Hong Cheang, Sonya V. Babu-Narayan, Sylvia Krupickova, Nitha Naqvi, Victor Tsang, Prathiba Chandershekar |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Pulmonary Artery 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Left coronary artery Interquartile range medicine.artery Lv dysfunction Internal medicine Bland White Garland Syndrome medicine Humans Radiology Nuclear Medicine and imaging In patient Child business.industry Infant Coronary ischemia medicine.disease Myocardial function Echocardiography Pulmonary artery Cardiology Cardiology and Cardiovascular Medicine business Surgical revascularization |
| Zdroj: | Journal of the American Society of Echocardiography. 33:622-630 |
| ISSN: | 0894-7317 |
| DOI: | 10.1016/j.echo.2019.12.014 |
| Popis: | We aimed to assess the change in global and regional myocardial function before and after surgical revascularization and their added value when compared with conventional measures in children with anomalous left coronary artery from the pulmonary artery (ALCAPA).Advanced echocardiographic assessment was performed pre- and postoperatively in 22 children with ALCAPA (eight male; median surgery age, 0.4 years; interquartile range, 0.21-1.05) and 22 healthy controls. Measurements included global and segmental longitudinal, radial, and circumferential two-dimensional speckle-tracking strain and postsystolic index.Global strains were lower in preoperative patients than in controls (longitudinal: -9% vs -21%; P .001; circumferential: -11% vs -21%; P .001; radial: 18% vs 60%; P .001) and improved postoperatively when compared with preoperative findings (longitudinal: -9% pre vs -16% post; P = .002, circumferential:-11% pre vs -17% post; P = .012, radial: 18% pre vs 53% post; P = .001). Preoperatively, patients with normal global systolic function on conventional echocardiography had significantly impaired global longitudinal and radial strain compared with healthy controls. Global mechanical dyssynchrony improved significantly postoperatively (longitudinal postsystolic index 43 pre vs 6 post, P .001; circumferential 15 pre vs 2 post, P = .001; radial 48 pre vs 5 post, P = .003). Despite overall improvement in most segments, global longitudinal and circumferential and segmental peak strain in some of the segments supplied by the ALCAPA remained postoperatively abnormal.This study shows that myocardial deformation indices were a more sensitive measure of LV dysfunction in patients before and after ALCAPA repair than conventional echocardiographic measures. We believe, therefore, they should be added to routine preoperative and serial postoperative follow-up assessment. |
| Databáze: | OpenAIRE |
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