Computed tomography as a predictor of the extent of the disease and surgical outcomes in ovarian cancer
| Autor: | Emre Baser, Kamil Yucel, Derya Kilic Sakarya, Burcu Kasap, Mehmet Hakan Yetimalar, Zeynep Ceren Cerci, Incim Bezircioglu |
|---|---|
| Přispěvatelé: | MÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kasap, Burcu |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Exploratory laparotomy medicine.medical_treatment Sensitivity and Specificity Adnexal mass Metastasis 03 medical and health sciences Computed Tomography Predictive Value of Tests Ovarian carcinoma Preoperative Care Ascites medicine Humans Peritoneal Neoplasms Neoplasm Staging Ovarian Neoplasms Laparotomy 030102 biochemistry & molecular biology Genitourinary system business.industry Carcinoma Obstetrics and Gynecology Cytoreduction Surgical Procedures Middle Aged medicine.disease Ovarian Carcinoma Radiologic Imaging Female Radiology medicine.symptom Prediction Tomography X-Ray Computed Complication business Ovarian cancer Cytoreductive Surgery |
| Zdroj: | Ginekologia Polska. 87:326-332 |
| ISSN: | 0017-0011 |
| DOI: | 10.5603/gp.2016.0002 |
| Popis: | WOS: 000378215000002 PubMed ID: 27304646 Objectives: The aim of the present study is to determine the predictive value of Computed Tomography (CT), alone or in combination with serum CA-125 levels, for preoperative staging, detection of the extent of the disease, and surgical complications in patients with ovarian carcinoma. Material and methods: One hundred and fourteen patients diagnosed with ovarian carcinoma following an exploratory laparotomy with a preoperative CT scan, performed between January 2007 and June 2013, were enrolled in the study. Preoperative CT and intraoperative surgical findings were compared using 14 parameters and predictions of CT for gastrointestinal, genitourinary, and cardiovascular complications. All radiological features and clinical characteristics were analyzed statistically. Results: CT and surgical findings correlated (sensitivity/specificity) as follows: uterine and tubal spread (66%/89%), cervical involvement (100%/80%), peritoneal nodulesincreased density-carcinomatosis (57%/93%), omental involvement (68%/95%), retroperitoneal involvement (25%/84%), ascites (85%/87%), perirectal and perivesical fat plan obliteration (43%/94%), liver metastasis (50%/91%), small and large bowel involvement (47%/95%), adnexal mass (94%/70%), and other metastases (47%/86%). Also, CT findings were found to be statistically insignificant for prediction of mesenteric involvement, bladder metastasis, and diaphragmatic involvement. The overall CT sensitivity and specificity at detecting intraoperative findings was 91% and 71%, respectively. We found a statistically significant correlation between intestinal involvement on CT and the necessity of additional surgical procedures. Conclusions: CT is a widely used imaging method in the preoperative evaluation of ovarian cancer. However, its predictive value, sensitivity and specificity differ, depending on the anatomical region. |
| Databáze: | OpenAIRE |
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