Effectiveness and safety of ultrasound-guided percutaneous microwave ablation for hepatic alveolar echinococcosis
| Autor: | Zhixin Wang, Yangdan Cairang, Jun-wei Han, Jing-jing Wang, Haining Fan, Kai-qaing Wang, Haijiu Wang, Xu Deng, Xiao-zhou Yang, Han-sheng Huang |
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| Rok vydání: | 2022 |
| Předmět: |
Adult
Male Hepatic alveolar echinococcosis Echinococcosis Hepatic medicine.medical_specialty Percutaneous business.industry Alveolar echinococcosis Microwave ablation Ultrasound guided Liver Catheter Ablation medicine Medical technology Humans Female Radiology Nuclear Medicine and imaging Radiology R855-855.5 Microwaves business Hepatic Alveolar Echinococcosis Ultrasonography Interventional Multilocular echinococcosis |
| Zdroj: | BMC Medical Imaging, Vol 22, Iss 1, Pp 1-9 (2022) |
| ISSN: | 1471-2342 |
| DOI: | 10.1186/s12880-022-00752-2 |
| Popis: | Background Microwave ablation (MWA) is a popular therapy for liver malignant tumor in recent years. Few studies have been conducted on its use in the treatment of hepatic alveolar echinococcosis (HAE). The study aims to evaluate the efficacy and safety of MWA in the treatment of HAE. Methods This study analyzed the data of 45 patients (mean age, 38 ± 2 years; 24 males) diagnosed with HAE and underwent MWA treatment between June 2014 to December 2019. The patients after MWA were examined by CT or MRI [follow-up: 32 months (IQR 23–48.5)] to determine whether the lesions were relapsed and to evaluate the therapeutic effect of MWA. The safety of MWA was evaluated by monitoring postoperative complications. Clinical data, such as patient demographics, imaging features of the lesions, relevant findings of laboratory tests before and after ablation, and information related to ablation, were collected and analyzed. Paired-sample t tests and paired-sample Wilcoxon signed-rank tests were used to compare relevant laboratory indicators before and after MWA. Results MWA was applied to 57 HAE lesions in 45 patients. The median size of lesions was 3.42 cm (IQR2.85–4.41). The rate of complete ablation was 100% (57/57). The median follow-up time was 32 months (IQR 23–48.5). The recurrence rate was 13% (6/45), and the median time of recurrence was 22 months. The rate of minor complications was 11.1% (5/45), and there were no major complications and deaths. Compared to preoperative, ALB, RBC, HBG, and PLT were decreased (p p p > 0.05). Conclusions MWA might be a safe and effective way to cure HAE. Meanwhile, it provides a new option and a new way of thinking about treatment for patients with HAE. |
| Databáze: | OpenAIRE |
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