Intrathecal baclofen in X-linked adrenoleukodystrophy
| Autor: | Howard L. Weiner, Mary Lynn Y. Chu, Debra A. Sala |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Baclofen Pediatrics medicine.medical_specialty medicine.medical_treatment Neurological disorder White matter chemistry.chemical_compound Developmental Neuroscience medicine Humans Spasticity Adrenoleukodystrophy Child Home Infusion Therapy Injections Spinal Chemotherapy Adrenocortical hormone Muscle Relaxants Central business.industry Infusion Pumps Implantable medicine.disease Dysphagia Surgery Treatment Outcome medicine.anatomical_structure Neurology chemistry Pediatrics Perinatology and Child Health Neurology (clinical) medicine.symptom business |
| Zdroj: | Pediatric Neurology. 24:156-158 |
| ISSN: | 0887-8994 |
| DOI: | 10.1016/s0887-8994(00)00250-2 |
| Popis: | X-linked adrenoleukodystrophy is a progressive neurodegenerative disorder involving the destruction of white matter in the brain and adrenocortical hormone deficiency. Clinical symptoms first appear between 4 and 8 years of age and include spasticity, visual loss, dysphagia, and seizures. In this report, continuous infusion of intrathecal baclofen was used to treat the severe spasticity of an 8-year-old patient with X-linked adrenoleukodystrophy. The improvement in this patient's quality of life, including the elimination of pain and the increased ease of care, suggests that intrathecal baclofen should be considered as part of the treatment strategy for spasticity associated with X-linked adrenoleukodystrophy and other neurodegenerative disorders in children and adults. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect