Homocysteine Levels and Oxidative Stress Parameters in Patients With Adult ADHD
| Autor: | Mehmet Asoglu, Sermin Nur Savas, Erdinc Cicek, Sehabettin Selek, İbrahim Fatih Karababa, Huseyin Bayazit, Turgay Ulas, Hasan Kandemir, Esra Ismet Cicek, Mahmut Kati |
|---|---|
| Přispěvatelé: | SELEK, ŞAHABETTİN |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Homocysteine Homocysteine levels medicine.disease_cause Antioxidants 03 medical and health sciences chemistry.chemical_compound Folic Acid 0302 clinical medicine Internal medicine Developmental and Educational Psychology medicine Humans In patient KARABABA İ. SAVAS S. Selek S. Cicek E. Cicek E. ASOGLU M. BAYAZIT H. KANDEMIR H. KATI M. ULAS T. -Homocysteine Levels and Oxidative Stress Parameters in Patients With Adult ADHD.- Journal of attention disorders cilt.21 ss.487-493 2017 Middle Aged Oxidants 030227 psychiatry Oxidative Stress Vitamin B 12 Clinical Psychology Endocrinology chemistry Attention Deficit Disorder with Hyperactivity Case-Control Studies Plasma homocysteine Female Psychology 030217 neurology & neurosurgery Oxidative stress |
| Zdroj: | Journal of Attention Disorders. 21:487-493 |
| ISSN: | 1557-1246 1087-0547 |
| Popis: | Objective: In our study, we aimed to evaluate the plasma homocysteine levels and oxidative stress parameters in patients with adult ADHD (A-ADHD). Method: Blood samples were taken from 32 A-ADHD patients and 32 controls enrolled in the study and plasma homocysteine, serum folate, vitamin B12, total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were determined. Results were compared between the groups. Results: Patients’ plasma homocysteine level was significantly lower and serum folate level was significantly higher than the controls. The means of plasma homocysteine and folate levels were statistically significantly different between the groups ( p < .05). However, a statistically significant difference was not detected between groups for mean serum vitamin B12, TAS, TOS, and OSI levels ( p > .05). Conclusion: Our study suggests that oxidative balance is not impaired in A-ADHD, and contrary to other psychiatric disorders, homocysteine levels were found to be lower. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|