Alkene synthesis: elimination of arenesulfinic acid from alkyl aryl sulfones using potassium trimethylsilanolate as base
| Autor: | Panayiotis A. Procopiou, Mark Ruston, Andrew A. Gray, Anthony G. M. Barrett, Charles Baker-Glenn |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
chemistry.chemical_classification
Base (chemistry) organic chemicals Aryl Potassium Organic Chemistry chemistry.chemical_element General Medicine Medicinal chemistry Biochemistry Sulfone Elimination reaction chemistry.chemical_compound Residue (chemistry) chemistry Alkene synthesis Drug Discovery Organic chemistry Potassium trimethylsilanolate Alkyl |
| Zdroj: | Tetrahedron Letters. 46:7427-7430 |
| ISSN: | 0040-4039 |
| Popis: | The use of potassium trimethylsilanolate as base to induce elimination of potassium arenesulfinate from alkyl aryl sulfones to produce E-alkenes is described. The reaction was appropriate for substrates containing a benzyl or allyl group α to the sulfone residue. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect