Effect of carbohydrate digestibility on appetite and its relationship to postprandial blood glucose and insulin levels
| Autor: | H. P. F. Peters, David J. Mela, H M Boers, H T W M van der Hijden, Peter Ravestein |
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| Přispěvatelé: | Nutrition & Health |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Blood Glucose Male insulin medicine.medical_specialty 030309 nutrition & dietetics media_common.quotation_subject medicine.medical_treatment Medicine (miscellaneous) 030209 endocrinology & metabolism Young Adult 03 medical and health sciences 0302 clinical medicine Double-Blind Method Polysaccharides Surveys and Questionnaires Internal medicine Blood plasma Dietary Carbohydrates medicine Humans glucose Glucans Pancreatic hormone media_common 2. Zero hunger Analysis of Variance 0303 health sciences Cross-Over Studies Nutrition and Dietetics Chemistry Insulin Appetite Middle Aged Carbohydrate Postprandial Period Diet appetite Glycemic index Endocrinology Postprandial Area Under Curve carbohydrate digestibility Linear Models Regression Analysis glycemic index Digestion Female |
| Zdroj: | European Journal of Clinical Nutrition European Journal of Clinical Nutrition, Nature Publishing Group, 2010, ⟨10.1038/ejcn.2010.189⟩ |
| ISSN: | 1476-5640 0954-3007 |
| DOI: | 10.1038/ejcn.2010.189 |
| Popis: | International audience; Background: 'Slowly digestible' carbohydrates have been claimed to reduce appetite via effects on postprandial glucose and insulin levels, but literature is inconsistent. The inconsistencies between studies might be explained by factors other than glycaemic effects per se, e.g., nutritional or physical properties. We tested this possibility by examining postprandial glucose, insulin and appetite responses to drinks differing only in rate and extent of digestibility of carbohydrates. This was accomplished by comparing different glucose polymers: maltodextrin (rapidly digestible) versus medium-chain pullulan (slowly but completely digestible) versus long-chain pullulan (indigestible). Subjects and Methods: In a randomized double-blind balanced crossover design, 35 subjects received drinks with 15g test carbohydrate polymers. Key outcome measures were appetite scores, digestibility (in vitro test and breath hydrogen), and (in a subset) glucose and insulin levels. Results: Digestibility, glucose and insulin data confirmed the rapid, slow, and non-digestible nature of the test carbohydrates. Despite its low digestibility, only long-chain pullulan reduced appetite versus the maltodextrin control, while the medium-chain pullulan did not. Conclusions: We conclude that glycemic responses per se have minimal effects on appetite, when tested in products only differing in carbohydrate digestibility rate and extent. |
| Databáze: | OpenAIRE |
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