Cloning and characterization of a novel RNA-binding protein SRL300 with RS domains
| Autor: | Kazumi Umeki, Taiki Tamaoki, Yutaka Miura, Sachiya Ohtaki, Kei Fujinaga, Yukiharu Sawada |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
DNA
Complementary Protein Conformation Molecular Sequence Data Biophysics RNA-binding protein Biology Biochemistry Protein structure Structural Biology Complementary DNA Genetics Animals Humans Amino Acid Sequence RNA Messenger Cloning Molecular Transcription factor Peptide sequence Homeodomain Proteins Cloning Messenger RNA RNA-Binding Proteins Molecular biology Rats TAF4 HeLa Cells |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1492:191-195 |
| ISSN: | 0167-4781 |
| DOI: | 10.1016/s0167-4781(00)00065-8 |
| Popis: | AT-rich element binding factor 1 (ATBF1) mRNA encodes a transcription factor implicated in neuronal differentiation. A cDNA for the protein that can bind the 5'-noncoding sequence of the ATBF1 mRNA was cloned. The deduced protein, termed SRL300, contains a unique RNA-binding region, two large RS domains and many phosphorylation sites. SRL300 protein was detected in both human and rat cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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