Current Concepts of Toxic Epidermal Necrolysis
| Autor: | Abele Dc, Rist Te |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Drug
medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions media_common.quotation_subject Disease medicine.disease_cause Methicillin Mice Nursing care medicine Animals Humans Child Skin media_common integumentary system Toxin business.industry General Medicine Staphylococcal Infections Conjunctivitis Prognosis medicine.disease Dermatology Toxic epidermal necrolysis Disease Models Animal Epidermal necrosis Child Preschool Stevens-Johnson Syndrome business Dermatitis Exfoliative |
| Zdroj: | Southern Medical Journal. 68:22-26 |
| ISSN: | 0038-4348 |
| DOI: | 10.1097/00007611-197501000-00007 |
| Popis: | Toxic epidermal necrolysis consists of two distinct clinical entities. The Ritter type, seen mostly in children under age 10, is the severest manifestation of staphylococcal disease. A toxin has been isolated which is postulated to be the cause for clinical lesions. High epidermal necrosis occurs. Treatment is with one of the penicillinase-resistant penicillins, and prognosis is good. The Lyell type is seen mostly in adults, is drug-related, and may be the severest form of the Stevens-Johnson syndrome. Full-thickness epidermal necrosis occurs. Treatment consists of withdrawing the offending drug. Good nursing care is essential. Prognosis is guarded. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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