Occult Hepatitis B Infection in Recent Immigrants to Italy: Occult B Infection in Immigrants
| Autor: | Coppola Nicola, Gaetano Scotto, Vincenzina Fazio |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Health (social science) Population Emigrants and Immigrants Gastroenterology 03 medical and health sciences Elevated alt 0302 clinical medicine Internal medicine Prevalence Humans Medicine 030212 general & internal medicine Hepatitis B Antibodies education Hepatitis education.field_of_study Hepatitis B Surface Antigens 030505 public health business.industry Public Health Environmental and Occupational Health Occult hepatitis B infection Hepatitis B medicine.disease Occult digestive system diseases Cross-Sectional Studies Italy DNA Viral 0305 other medical science business Viral load |
| Zdroj: | Journal of Community Health. 45:357-362 |
| ISSN: | 1573-3610 0094-5145 |
| Popis: | This study determined the prevalence and clinical features of occult hepatitis B infection (OBI) in a population of recent immigrants to Italy. Two hundred-five immigrants were tested for HBV-infection and were classified as seropositive-OBI or false-OBI. Biochemical/virological activities and imaging diagnostics were determined in anti-HBc-positive subjects. Among the tested subjects, 39.0% were anti-HBc-positive/HBsAg-negative; 11.2% had persistently normal ALT levels with mild detectable HBV-DNA, seropositive-OBI; 6.2% had slightly elevated ALT and positive serum HBV-DNA with a mean level of viral load: 3275 copies/mL-false-OBI. The total prevalence of OBI was 6.8%; 4.4% were seropositive-OBI and 2.4% were false-OBI. Diagnosis by echo-tomography was achieved in 35.7% OBI subjects with alterations of the hepatic echo-texture. We found a moderate prevalence of occult hepatitis B-infection in immigrants. Frequently, these subjects present false-OBI. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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