Physicochemical and biological characterizations of distinct strains of the transmissible mink encephalopathy agent
| Autor: | R. A. Bessen, R. F. Marsh |
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| Rok vydání: | 1994 |
| Předmět: |
Time Factors
Chemical Phenomena PrPSc Proteins Prions Transmissible mink encephalopathy agent animal diseases General Biochemistry Genetics and Molecular Biology Prion Diseases Cricetinae biology.animal Biological property Endopeptidases Animals Mink Syrian hamsters Transmissible mink encephalopathy Mesocricetus biology Chemistry Physical Scrapie agent biology.organism_classification Virology sense organs General Agricultural and Biological Sciences |
| Zdroj: | Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 343:413-414 |
| ISSN: | 1471-2970 0962-8436 |
| Popis: | Inoculation of the Stetsonville, Wisconsin source of transmissible mink encephalopathy (TME) into Syrian hamsters has identified two strains of the tme agent having distinct biological properties and producing disease-specific prion proteins (PrP tme ) having different physicochemical properties. Although several strains of the sheep scrapie agent have been identified in Great Britain, this is the first indication that agents producing transmissible spongiform encephalopathies in the United States also are capable of producing distinct strains. |
| Databáze: | OpenAIRE |
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