Factors associated with renal impairment in Chinese patients with non-valvular AF and without an established renal disease: a cross-sectional study
| Autor: | Youmei Shen, Jing Wang, Hongwu Chen, Mingfang Li, Minglong Chen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty China Cross-sectional study Renal function 030209 endocrinology & metabolism Comorbidity 030204 cardiovascular system & hematology 03 medical and health sciences Electrocardiography 0302 clinical medicine Risk Factors Internal medicine Atrial Fibrillation medicine Humans Renal Insufficiency Stroke Aged Ejection fraction business.industry Age Factors Atrial fibrillation General Medicine Middle Aged medicine.disease Cross-Sectional Studies Logistic Models Embolism Cardiovascular Diseases Heart failure Cardiology Female business Kidney disease Glomerular Filtration Rate |
| Zdroj: | Postgraduate medicine. 132(5) |
| ISSN: | 1941-9260 |
| Popis: | BACKGROUND Renal impairment and atrial fibrillation (AF) often coexist. However, risk factors associated with renal impairment in AF patients have not been studied in a large population. Accordingly, this study investigated clinical factors associated with renal impairment in AF patients. METHODS From January 2012 to December 2016, 2,298 inpatients with non-valvular AF (NVAF) mainly for catheter ablation were enrolled in this cross-sectional study. Data collection included past medical history, echocardiography measurements, current medicine use and biochemical results. The estimated glomerular filtration rate (eGFR) was calculated using the abbreviated Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Renal impairment was defined as a history of chronic kidney disease or an eGFR ≤90 ml/min/1.73 m2. Multivariate logistic regression was conducted to evaluate the relationship between the factors screened and eGFR. RESULTS The mean eGFR was 88.6 ± 17.1 ml/min/1.73 m2. The overall prevalence of renal impairment was 47.4%. Multivariate logistic regression showed that factors associated with renal impairment were age (OR: 1.12; 95% CI: 1.11-1.14), non-paroxysmal AF (OR: 1.28; 95% CI: 1.04-1.58), use of angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB) (OR: 1.58; 95% CI: 1.28-1.95), congestive heart failure (OR: 1.80; 95% CI: 1.05-3.07), left ventricular ejection fraction (LVEF) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|