Endocytoscopic microvasculature evaluation is a reliable new diagnostic method for colorectal lesions (with video)
| Autor: | Yuichi Mori, Masashi Misawa, Naoya Toyoshima, Hiroki Nakamura, Haruhiro Inoue, Noriyuki Ogata, Seiko Hayashi, Tomokazu Hisayuki, Makoto Kutsukawa, Toyoki Kudo, Yoshiki Wada, Fumio Ishida, Shin-ei Kudo, Yasuharu Maeda, Shinichi Kataoka, Kunihiko Wakamura, Hideyuki Miyachi, Hiromasa Oikawa, Takemasa Hayashi |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Diagnostic methods Time Factors Biopsy Pit pattern Diagnosis Differential Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Medical diagnosis Retrospective Studies Invasive carcinoma Microscopy Confocal business.industry Microcirculation Gastroenterology Reproducibility of Results Retrospective cohort study Colonoscopy Optical Biopsy Middle Aged University hospital Capillaries Hyperplastic Polyp ROC Curve Female Radiology business Colorectal Neoplasms Follow-Up Studies |
| Zdroj: | Gastrointestinal endoscopy. 82(5) |
| ISSN: | 1097-6779 |
| Popis: | Background We previously reported on the efficacy of endocytoscopic classification (EC-C). However, the correlation of the endocytoscopic vascular (EC-V) pattern with diagnoses was unclear. Objective To assess the diagnostic accuracy of the EC-V pattern for colorectal lesions. Design Retrospective. Setting A university hospital. Patients Patients who underwent endocytoscopy between January 2010 and March 2013. Intervention We evaluated 198 consecutive lesions according to the EC-V pattern (EC-V1, obscure surface microvessels; EC-V2, clearly observed surface microvessels of a uniform caliber and arrangement; and EC-V3, dilated surface microvessels of a nonhomogeneous caliber or arrangement). Main Outcome Measurements The diagnostic accuracy for predicting hyperplastic polyps and invasive cancer were compared between the EC-V pattern and other modalities (narrow-band imaging, pit pattern, and EC-C). Results The sensitivity, specificity, and accuracy of the EC-V1 pattern for diagnosing hyperplastic polyps were 95.5%, 99.4%, and 99.0%, respectively. The sensitivity, specificity, and accuracy of the EC-V3 pattern for diagnosing invasive cancer were 74.6%, 97.2%, and 88.6%, respectively. The diagnostic accuracy of the EC-V pattern for predicting hyperplastic polyps was comparable to the other modalities. For predicting invasive cancer, the EC-V pattern was comparable to narrow-band imaging and pit pattern, although EC-C was slightly more accurate ( P = .04). In the substudy, the diagnosis time by using the EC-V pattern was shorter than that with the EC-C pattern ( P Limitations A single-center, retrospective study. Conclusions The EC-V pattern saved more time than the EC-C pattern and had a diagnostic ability comparable to that of other optical biopsy modalities. |
| Databáze: | OpenAIRE |
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