Association of weekend effect with early mortality in severe sepsis patients over time
| Autor: | Raghu Seethala, Peter C. Hou, Yen-Tao Hsu, Gyorgy Frendl, Ran-Chou Chen, Imoigele P. Aisiku, Shuo-Ming Ou, Yu-Ning Shih, Chia-Jen Shih, Yung Tai Chen |
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| Rok vydání: | 2016 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Time Factors Weekend effect education Taiwan Confidential interval Sepsis 03 medical and health sciences Young Adult 0302 clinical medicine Patient Admission Clinical endpoint Odds Ratio Medicine Humans 030212 general & internal medicine Hospital Mortality Intensive care medicine Severe sepsis Aged Retrospective Studies Aged 80 and over business.industry Mortality rate 030208 emergency & critical care medicine Odds ratio Middle Aged medicine.disease Hospitalization Infectious Diseases Emergency medicine Female Health Services Research business Database research |
| Zdroj: | The Journal of infection. 74(4) |
| ISSN: | 1532-2742 |
| Popis: | Summary Background The aim of this study is to investigate the "weekend effect" and early mortality of patients with severe sepsis. Methods Using the Taiwanese National Healthcare Insurance Research Database, all patients who were hospitalized for the first time with an episode of severe sepsis between January 2000 and December 2011 were identified and the short-term mortality of patients admitted on weekdays was compared to those admitted on weekends. The primary endpoint was 7-day mortality. The secondary endpoints were 14 and 28-day mortality. Results A total of 398,043 patients were identified to have had the diagnosis of severe sepsis. Compared with patients admitted on weekends, patients admitted on weekdays had a lower 7-day mortality rate (adjusted odds ratio [OR] 0.89, 95% confidential interval [CI] 0.87–0.91), 14-day mortality rate (adjusted OR 0.92, 95% CI 0.90–0.93), and 28-day mortality rate (adjusted OR 0.97, 95% CI 0.95–0.98). This "weekend effect" was maintained every year throughout the 11-year study period. Conclusions Patients with severe sepsis are more likely to die in the hospital if they were admitted on weekends than if they were admitted on weekdays. |
| Databáze: | OpenAIRE |
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