Preoperative liver dysfunction influences blood product administration and alterations in circulating haemostatic markers following ventricular assist device implantation
| Autor: | Christian Bermudez, Joshua R. Woolley, Jeffrey J. Teuteberg, William R. Wagner, Jay K. Bhama, Kathleen L. Lockard, N. Kunz, Robert L. Kormos |
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| Rok vydání: | 2014 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.medical_specialty medicine.medical_treatment law.invention Cohort Studies Liver disease Blood product law Internal medicine Fibrinolysis medicine Cardiopulmonary bypass Humans Blood Transfusion Cardiac Surgical Procedures Hemostatic function Adverse effect Subclinical infection Aged Heart Failure business.industry Platelet Count Liver Diseases Hemodynamics General Medicine Transplantation and Mechanical Circulatory Support Middle Aged medicine.disease Surgery body regions Ventricular assist device Multivariate Analysis Cardiology Heart Transplantation Female Heart-Assist Devices Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 47(3) |
| ISSN: | 1873-734X |
| Popis: | OBJECTIVES: Preoperative liver dysfunction may influence haemostasis following ventricular assist device (VAD) implantation. The Model for End-stage Liver Disease (MELD) score was assessed as a predictor of bleeding and levels of haemostatic markers in patients with currently utilized VADs. METHODS: Sixty-three patients (31 HeartMate II, 15 HeartWare, 17 Thoratec paracorporeal ventricular assist device) implanted 2001–11 were analysed for preoperative liver dysfunction (MELD) and blood product administration. Of these patients, 21 had additional blood drawn to measure haemostatic marker levels. Cohorts were defined based on high (≥18.0, n= 7) and low ( |
| Databáze: | OpenAIRE |
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