Willingness to participate in future HIV prevention trials in Beira, Mozambique
| Autor: | Nienke J. Veldhuijzen, Janneke van de Wijgert, Arlinda Zango, Ivete Meque, Paul J. Feldblum, Karine Dubé, Fidelina Cumbe, Lotte Bierhuizen |
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| Přispěvatelé: | Epidemiology and Data Science, CCA - Innovative therapy |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Evening Adolescent Sexual Behavior HIV Infections Pre-exposure prophylaxis Young Adult Acquired immunodeficiency syndrome (AIDS) Virology Medicine Humans Mozambique Preventive healthcare Gynecology Motivation business.industry Vaginal microbicide Public Health Environmental and Occupational Health General Medicine medicine.disease Vaginal ring Administration Intravaginal Infectious Diseases Cross-Sectional Studies Sexual Partners Hormonal contraception HIV prevention Mozambique pre-exposure prophylaxis vaccine vaginal microbicide willingness to participate Vaginal Creams Foams and Jellies Patient Compliance Female business Blood drawing Demography |
| Zdroj: | African Journal of AIDS Research; Vol 13, No 4 (2014) African Journal of AIDS Research, 13(4), 393-398. Taylor and Francis Ltd. Meque, I, Dube, K, Bierhuizen, L, Zango, A, Veldhuijzen, N J, Cumbe, F, Feldblum, P J & van de Wijgert, J H 2014, ' Willingness to participate in future HIV prevention trials in Beira, Mozambique ', African Journal of AIDS Research, vol. 13, no. 4, pp. 393-398 . https://doi.org/10.2989/16085906.2014.985239 |
| ISSN: | 1727-9445 1608-5906 |
| Popis: | In preparation for trials of new HIV prevention methods, willingness to participate (WTP) was assessed in Beira, Mozambique. A totla of 1 019 women participating in an HIV incidence study, and 97 men participating in a separate WTP survey, were interviewed. When comparing the answers to questions that were identical in the two studies, WTP was higher among women than men for all prevention methods. Among women, WTP was highest for trials evaluating daily oral pre-exposure prophylaxis (PrEP; 84.4% reporting very likely to participate), followed by vaccination (77.8%), daily vaginal gel use (67.7%), coital vaginal gel use (67.1%) and monthly vaginal ring use (47.7%). Among men, WTP was highest for trials evaluating vaccination (57.6%), followed by daily vaginal gel use for female sexual partners (52.5%), daily oral PrEP (49.5%), coital vaginal gel use for female sexual partners (46.4%) and monthly vaginal ring use for female sexual partners (39.4%). Among men, the most important motivators for trial participation were social benefits, whereas personal risks (most notably receiving injections and/or blood draws) were deterrents; this was not assessed in women. Other important lessons learnt are that male circumcision and antiretroviral drugs were not generally recognised as ways to prevent HIV, that having to use hormonal contraception during trial participation will likely reduce WTP, and that evening clinics are not likely to be popular. The barriers reported in this and other studies may be challenging but are not impossible to overcome.Keywords: HIV prevention, Mozambique, pre-exposure prophylaxis, vaccine, vaginal microbicide, willingness to participate |
| Databáze: | OpenAIRE |
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