Composite mucinous and granulosa-cell tumor of ovary: case report of a unique neoplasm
| Autor: | Peter Russell, Patricia Bannatyne, Anna Price, Peter Elliott |
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| Rok vydání: | 1990 |
| Předmět: |
endocrine system
Cell type Pathology medicine.medical_specialty Granulosa cell Ovary Histogenesis Biology Hysterectomy Pathology and Forensic Medicine Pleomorphic adenoma Neoplasms Multiple Primary Ovarian tumor medicine Humans Cyst Granulosa Cell Tumor Ovarian Neoplasms Obstetrics and Gynecology Middle Aged medicine.disease Adenocarcinoma Mucinous medicine.anatomical_structure Adenocarcinoma Female |
| Zdroj: | International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 9(4) |
| ISSN: | 0277-1691 |
| Popis: | A 63-year-old woman presented with signs and symptoms of an estrogen-producing ovarian tumor. At laparotomy, this tumor proved to be a multilocular right ovarian mass 20 cm in greatest diameter. The cystic spaces were lined by typical benign mucinous epithelium of the endocervical type, while the greatly thickened cyst walls contained a diffuse proliferation of granulosa cells. These two disparate components were intimately mixed at a variably complex interface to form a composite tumor. While composite tumors showing sex cord-stromal and epithelial elements are well documented, they have all, to date, been of moderately to poorly differentiated androblastomatous or Sertoli-Leydig cell type, associated with heterologous mucinous elements of intestinal differentiation. The combination of granulosa-cell tumor with mucinous elements of endocervical or mullerian type has not hitherto been reported and is of uncertain histogenesis. |
| Databáze: | OpenAIRE |
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