Tissue Doppler-derived index of left ventricular filling pressure, E/E', predicts survival of patients with non-valvular atrial fibrillation
| Autor: | Shin Mizoguchi, Junichi Yoshikawa, Iku Toda, Hiroyuki Okura, Yuko Takada, Kazuya Iwata, Haruyuki Taguchi, Kiyoshi Yoshida, Tomoichiro Kubo |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Heart disease Cardiovascular Medicine Doppler echocardiography Ventricular Dysfunction Left Internal medicine Atrial Fibrillation medicine Humans cardiovascular diseases Survival analysis Aged Chi-Square Distribution medicine.diagnostic_test business.industry Atrial fibrillation Odds ratio Prognosis medicine.disease Survival Analysis Echocardiography Doppler Confidence interval Heart failure cardiovascular system Cardiology Regression Analysis Female Cardiology and Cardiovascular Medicine business Chi-squared distribution |
| Zdroj: | Heart. 92:1248-1252 |
| ISSN: | 1355-6037 |
| DOI: | 10.1136/hrt.2005.082594 |
| Popis: | To investigate whether the ratio of early transmitral flow velocity (E) to early diastolic mitral annular velocity (E') predict prognosis in patients with non-valvular atrial fibrillation.230 patients with non-valvular atrial fibrillation were enrolled and studied. According to E/E' value, patients were divided into groups with lower (group A with E/E'or= 15) and higher (group B with E/E'15) E/E'.During follow up (average 245 days), 21 (9.1%) deaths were documented. All cause death (15/90 (16.7%) v 6/140 (4.3%)), cardiac death (10 (11.1%) v 2 (1.4%)) and congestive heart failure (16 (17.8%) v 8 (5.7%)) were more common in group B than in group A (all p0.01). A Kaplan-Meier survival curve showed that the cumulative survival rate was significantly lower in group B than in group A (log rank p = 0.0013). By multivariate logistic regression analysis, E/E' (chi(2) = 4.47, odds ratio (OR) 1.05, 95% confidence interval (CI) 1.01 to 1.11, p = 0.03) and age (chi(2) = 6.45, OR 1.06, 95% CI 1.01 to 1.11, p = 0.02) were independent predictors of mortality.The Doppler-derived index of left ventricular filling pressure, E/E', is a powerful predictor of the clinical outcome of patients with non-valvular atrial fibrillation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|