Assessment of sarcopenia in virally suppressed HIV-infected Asians receiving treatment
| Autor: | Nor Syuhada Ahmad Bashah, Megan McStea, Maw Pin Tan, Siti Azdiah Abdul Aziz, Shahrul Bahyah Kamaruzzaman, Helmi Sulaiman, Sharifah Faridah Syed Omar, Adeeba Kamarulzaman, Sasheela Ponnampalavanar, Meng Li Chong, Reena Rajasuriar, Iskandar Azwa |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male Percentile medicine.medical_specialty Sarcopenia Anti-HIV Agents Immunology HIV Infections Health outcomes 03 medical and health sciences Grip strength 0302 clinical medicine Asian People Risk Factors Internal medicine medicine Prevalence Immunology and Allergy Humans 030212 general & internal medicine Muscle Strength Aged Aged 80 and over business.industry Age Factors Middle Aged medicine.disease 030112 virology Middle age Walking Speed Preferred walking speed Infectious Diseases Cohort Female business Viral load |
| Zdroj: | AIDS (London, England). 32(8) |
| ISSN: | 1473-5571 |
| Popis: | Objectives: In a clinic-based, treated HIV-infected cohort, we identified individuals with sarcopenia and compared with age, sex and ethnically matched controls; and investigated associated risk factors and health outcomes. Design: Sarcopenia (age-related muscle loss) causes significant morbidity to the elderly, leading to frequent hospitalizations, disability and death. Few have characterized sarcopenia in the HIV-infected who experience accelerated aging. Methods: Sarcopenia was defined as low muscle mass with weak grip strength and/or slow gait speed using lower 20th percentiles of controls. Multivariate logistic and linear regression analyses were used to explore risk factors and health-related outcomes associated with sarcopenia among HIV-infected individuals. Results: We recruited 315 HIV-infected individuals aged at least 25 years with at least 1-year history of undetectable viral load on treatment (HIV RNA |
| Databáze: | OpenAIRE |
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