Eosinophilic Sialodochitis: A Type of Chronic Obstructive Sialadenitis Related to Allergy
Autor: | Deng-gao Liu, Guang-Yan Yu, Yan Chen, Wen-Xuan Zhu |
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Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Eotaxin Adult Male medicine.medical_specialty Adolescent Sialodochitis Immunoglobulin E Gastroenterology Salivary Glands Sialadenitis 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine Metaplasia Eosinophilic Eosinophilia medicine Hypersensitivity Humans music music.instrument Interleukin-13 biology Salivary gland business.industry Eosinophil Middle Aged medicine.disease Follicular hyperplasia Blood Cell Count 030104 developmental biology medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Chemokines CC Chronic Disease biology.protein Female Tryptases Interleukin-4 medicine.symptom business |
Zdroj: | The LaryngoscopeBIBLIOGRAPHY. 131(3) |
ISSN: | 1531-4995 |
Popis: | OBJECTIVES To investigate the clinical, laboratory, radiological, histopathological, and immunohistochemical features, and the expression of allergy-related cytokines in eosinophilic sialodochitis (ES). METHODS Thirty-eight patients diagnosed with chronic obstructive sialadenitis (COS) who had undergone glandular excision or incisional biopsy were enrolled. Seventeen patients with comorbid atopic disease and increased ductal tissue eosinophils comprised the ES group, while 21 patients comprised the COS group. The clinicopathological features and allergy-related cytokine expression were compared between groups. RESULTS The ES group frequently involved multiple, bilateral major salivary glands, and the number of glands was significantly greater than the COS group (2.8 ± 1.1 vs. 1.2 ± 0.4, P |
Databáze: | OpenAIRE |
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