Eosinophilic Sialodochitis: A Type of Chronic Obstructive Sialadenitis Related to Allergy

Autor: Deng-gao Liu, Guang-Yan Yu, Yan Chen, Wen-Xuan Zhu
Rok vydání: 2020
Předmět:
Zdroj: The LaryngoscopeBIBLIOGRAPHY. 131(3)
ISSN: 1531-4995
Popis: OBJECTIVES To investigate the clinical, laboratory, radiological, histopathological, and immunohistochemical features, and the expression of allergy-related cytokines in eosinophilic sialodochitis (ES). METHODS Thirty-eight patients diagnosed with chronic obstructive sialadenitis (COS) who had undergone glandular excision or incisional biopsy were enrolled. Seventeen patients with comorbid atopic disease and increased ductal tissue eosinophils comprised the ES group, while 21 patients comprised the COS group. The clinicopathological features and allergy-related cytokine expression were compared between groups. RESULTS The ES group frequently involved multiple, bilateral major salivary glands, and the number of glands was significantly greater than the COS group (2.8 ± 1.1 vs. 1.2 ± 0.4, P
Databáze: OpenAIRE