A Case of Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome Responsive to Tonsillectomy in Japan
| Autor: | Noriyuki Nakashima, Satoshi Ikegami, Yuki Egawa, Kohei Yamahara, Kana Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
030203 arthritis & rheumatology
medicine.medical_specialty PFAPA syndrome business.industry medicine.medical_treatment Case Report General Medicine medicine.disease lcsh:Otorhinolaryngology Dermatology Complete resolution lcsh:RF1-547 Pharyngitis Tonsillectomy 03 medical and health sciences 0302 clinical medicine Prednisone Periodic fever medicine Cervical adenitis 030212 general & internal medicine medicine.symptom business Stomatitis medicine.drug |
| Zdroj: | Case Reports in Otolaryngology Case Reports in Otolaryngology, Vol 2019 (2019) |
| ISSN: | 2090-6773 2090-6765 |
| Popis: | Adult-onset periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is a rare condition, having been reported in only three patients in Japan till date. While almost all pediatric PFAPA patients respond well to tonsillectomy, some European studies have reported that tonsillectomy may be ineffective for adult-onset PFAPA. All the Japanese patients with adult-onset PFAPA had been treated orally so far (cimetidine with or without prednisone), instead of tonsillectomy. We reported a case involving a 37-year-old Japanese man with PFAPA syndrome who presented with a history of febrile episodes associated with pharyngitis, cervical adenitis, and aphthous stomatitis for one year. The patient had been undergoing oral medication therapy without any significant improvement. Tonsillectomy was performed for the patient, and complete resolution of PFAPA was achieved. Our experience suggests that a tonsillectomy is a viable option for the treatment of adult-onset PFAPA. |
| Databáze: | OpenAIRE |
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