The relationship between positive peritoneal cytology and the prognosis of patients with FIGO stage I/II uterine cervical cancer
| Autor: | Aki Tanaka, Satomi Komeda, Munetaka Takekuma, Shiho Kuji, Yasuyuki Hirashima, Nobutaka Takahashi, Masakazu Abe |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Adenosquamous carcinoma Gastroenterology Cervix Internal medicine medicine Carcinoma Radical hysterectomy Radical Hysterectomy Lymph node Pathological Gynecology Cervical cancer Peritoneal cytology business.industry Obstetrics and Gynecology General Medicine Uterine cervical cancer medicine.disease Prognosis medicine.anatomical_structure Oncology Adenocarcinoma Original Article business |
| Zdroj: | Journal of Gynecologic Oncology |
| ISSN: | 2005-0399 2005-0380 |
| Popis: | OBJECTIVE The purpose of this study was to assess whether peritoneal cytology has prognostic significance in uterine cervical cancer. METHODS Peritoneal cytology was obtained in 228 patients with carcinoma of the uterine cervix (International Federation of Gynecology and Obstetrics [FIGO] stages IB1-IIB) between October 2002 and August 2010. All patients were negative for intraperitoneal disease at the time of their radical hysterectomy. The pathological features and clinical prognosis of cases of positive peritoneal cytology were examined retrospectively. RESULTS Peritoneal cytology was positive in 9 patients (3.9%). Of these patients, 3/139 (2.2%) had squamous cell carcinoma and 6/89 (6.7%) had adenocarcinoma or adenosquamous carcinoma. One of the 3 patients with squamous cell carcinoma who had positive cytology had a recurrence at the vaginal stump 21 months after radical hysterectomy. All of the 6 patients with adenocarcinoma or adenosquamous carcinoma had disease recurrence during the follow-up period: 3 with peritoneal dissemination and 2 with lymph node metastases. There were significant differences in recurrence-free survival and overall survival between the peritoneal cytology-negative and cytology-positive groups (log-rank p |
| Databáze: | OpenAIRE |
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