Relationship between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia occurrence rate in community-dwelling Chinese adults
Autor: | Mengjun Chen, Danhong Fang, Na Wang |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty China Sarcopenia Endocrinology Diabetes and Metabolism Clinical Biochemistry Clinical nutrition Logistic regression Gastroenterology Triglyceride 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology High-density lipoprotein High-density lipoprotein cholesterol Internal medicine Surveys and Questionnaires medicine Odds Ratio Humans 030212 general & internal medicine lcsh:RC620-627 Triglycerides Aged Community-dwelling Chinese adults business.industry Cholesterol Research Biochemistry (medical) Cholesterol HDL Odds ratio Middle Aged medicine.disease Confidence interval lcsh:Nutritional diseases. Deficiency diseases Cross-Sectional Studies Logistic Models chemistry ROC Curve Multivariate Analysis Female business human activities 030217 neurology & neurosurgery |
Zdroj: | Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-7 (2020) Lipids in Health and Disease |
Popis: | Background A study conducted on elderly Korean men showed that a high serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio was associated with a high risk of developing sarcopenia. We aimed to determine such an association in community-dwelling Chinese adults. Methods From May 2016 to August 2017, we conducted a cross-sectional study on Chinese adults at the First Affiliated Hospital of Wenzhou Medical University. Univariate and multivariate logistic regression analyses were applied to evaluate a possible relationship between TG/HDL-C ratio and sarcopenia occurrence. Results We included 2613 adults in this study, with 13.85% presenting with sarcopenia. The odds ratios (ORs) for TG and HDL-C were 0.67 (95% confidence interval [CI]: 0.51–0.87), and 1.97 (95% CI: 1.49–2.61), respectively. Moreover, TG/HDL-C ratio was independently associated with sarcopenia status (OR: 0.63; 95% CI: 0.49–0.81). Conclusions We found that TG and HDL-C were, respectively, negatively and positively associated with sarcopenia occurrence rate in community-dwelling Chinese adults. However, a negative association was found between sarcopenia occurrence rate and TG/HDL-C ratio. |
Databáze: | OpenAIRE |
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