Relationship between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia occurrence rate in community-dwelling Chinese adults

Autor: Mengjun Chen, Danhong Fang, Na Wang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
China
Sarcopenia
Endocrinology
Diabetes and Metabolism
Clinical Biochemistry
Clinical nutrition
Logistic regression
Gastroenterology
Triglyceride
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Endocrinology
High-density lipoprotein
High-density lipoprotein cholesterol
Internal medicine
Surveys and Questionnaires
medicine
Odds Ratio
Humans
030212 general & internal medicine
lcsh:RC620-627
Triglycerides
Aged
Community-dwelling Chinese adults
business.industry
Cholesterol
Research
Biochemistry (medical)
Cholesterol
HDL
Odds ratio
Middle Aged
medicine.disease
Confidence interval
lcsh:Nutritional diseases. Deficiency diseases
Cross-Sectional Studies
Logistic Models
chemistry
ROC Curve
Multivariate Analysis
Female
business
human activities
030217 neurology & neurosurgery
Zdroj: Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-7 (2020)
Lipids in Health and Disease
Popis: Background A study conducted on elderly Korean men showed that a high serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio was associated with a high risk of developing sarcopenia. We aimed to determine such an association in community-dwelling Chinese adults. Methods From May 2016 to August 2017, we conducted a cross-sectional study on Chinese adults at the First Affiliated Hospital of Wenzhou Medical University. Univariate and multivariate logistic regression analyses were applied to evaluate a possible relationship between TG/HDL-C ratio and sarcopenia occurrence. Results We included 2613 adults in this study, with 13.85% presenting with sarcopenia. The odds ratios (ORs) for TG and HDL-C were 0.67 (95% confidence interval [CI]: 0.51–0.87), and 1.97 (95% CI: 1.49–2.61), respectively. Moreover, TG/HDL-C ratio was independently associated with sarcopenia status (OR: 0.63; 95% CI: 0.49–0.81). Conclusions We found that TG and HDL-C were, respectively, negatively and positively associated with sarcopenia occurrence rate in community-dwelling Chinese adults. However, a negative association was found between sarcopenia occurrence rate and TG/HDL-C ratio.
Databáze: OpenAIRE
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