Can magnetic resonance spectroscopy differentiate endometrial cancer?
| Autor: | Chunrun Yang, Yinghui Xin, Xichao Sun, Caixia Fu, Changzhong Li, Yuanyuan Zong, Jie Zhang, Qingwei Liu, Xue Han, Shifeng Cai |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
In vivo magnetic resonance spectroscopy medicine.medical_specialty Magnetic Resonance Spectroscopy Coefficient of variation Tumour stage Choline Diagnosis Differential Biomarkers Tumor medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Aged Neoplasm Staging medicine.diagnostic_test business.industry Endometrial cancer Reproducibility of Results Magnetic resonance imaging General Medicine Nuclear magnetic resonance spectroscopy Middle Aged medicine.disease Magnetic Resonance Imaging Endometrial Neoplasms Preoperative Period Female Radiology business Follow-Up Studies |
| Zdroj: | European Radiology. 24:2552-2560 |
| ISSN: | 1432-1084 0938-7994 |
| Popis: | To investigate whether the choline-containing compounds (Cho) obtained from three-dimensional 1H magnetic resonance (MR) spectroscopy can differentiate endometrial cancer (ECa) from benign lesions in endometria or in submucosa (BLs-ESm) and is associated with the aggressiveness of ECa. Fifty-seven patients (ECa, 38; BLs-ESm, 19) underwent preoperative multi-voxel MR spectroscopy at 3.0 T. The ratio of the sum of the Cho peak integral to the sum of the unsuppressed water peak integral (Cho/water) and the coefficient of variation (CV) used to describe the variability of Cho/water in one lesion were calculated. Mean Cho/water (±standard deviation [SD]) was (3.02 ± 1.43) × 10−3 for ECa and (1.68 ± 0.33) × 10−3 for BLs-ESm (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink