Fluid intake and industrial processing in apple juice induced chronic non-specific diarrhoea
| Autor: | R. Hartemink, Y.F. Ghoos, C.M.F. Kneepkens, J. H. Hoekstra, J.H.L. van den Aker |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1995 |
| Předmět: |
Diarrhea
Male Malabsorption Food Handling Drinking complex mixtures Excretion chemistry.chemical_compound Breath tests Food Chemistry and Microbiology Medicine Monosaccharide Humans Food science Fluid intake VLAG Stable isotopes chemistry.chemical_classification Cross-Over Studies Gastric emptying business.industry fungi Infant Fructose Carbohydrate biochemical phenomena metabolism and nutrition medicine.disease equipment and supplies Crossover study chemistry Gastric Emptying Levensmiddelenchemie en -microbiologie Child Preschool Fruit Pediatrics Perinatology and Child Health Chronic Disease bacteria Female medicine.symptom business Child Nutritional Physiological Phenomena Chronic diarrhoea Hydrogen Research Article |
| Zdroj: | Archives of disease in childhood 73 (1995) Archives of disease in childhood, 73, 126-130 |
| ISSN: | 0003-9888 |
| DOI: | 10.1136/adc.73.2.126 |
| Popis: | Dietary factors have been shown to contribute to the occurrence or persistence of chronic non-specific diarrhoea (CNSD). Among these are low dietary fat, high fluid consumption, and the consumption of apple juice. Prompted by the clinical impression that freshly pressed and unprocessed ('cloudy') apple juice was less likely to induce diarrhoea than normal, enzymatically processed ('clear') apple juice, both juices were compared in terms of carbohydrate malabsorption, gastric emptying, and effects on defecation patterns. Clear and cloudy apple juice differ in their fibre and non-absorbable monosaccharide and oligosaccharide contents. Ten healthy children aged 3.6 to 5.9 years ingested 10 ml/kg of clear and cloudy apple juice; in five of them it was enriched with 40 mg of [1-13C]-glycine. Clear apple juice resulted in increased (> or = 20 ppm) breath hydrogen excretion in 8/10, compared with 5/10 after cloudy apple juice; peak breath hydrogen was higher in the clear apple juice group (35 (4) and 18 (3) ppm, respectively). Gastric emptying as determined by means of labelled breath carbon dioxide (13CO2) excretion was similar with both juices. In a four week crossover clinical trial 12 children, formerly diagnosed as having CNSD, were given extra clear fluids (excluding fruit juices; > or = 50% over basal consumption), clear apple juice, or cloudy apple juice, for five day periods. Extra fluids and cloudy apple juice did not influence stool frequency and consistency compared with the basal period. In contrast, clear apple juice significantly promoted diarrhoea. It is suggested that, in addition to fructose, the increased availability of non-absorbable monosaccharides and oligosaccharides as a result of the enzymatic processing of apple pulp is an important aetiological factor in apple juice induced CNSD. |
| Databáze: | OpenAIRE |
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