Isolation of Proteus mirabilis from Clinical Urogenital Specimens: A Study of the Antibiotic Susceptibility Patterns of 392 Consecutively Isolated Strains in Jos, Nigeria

Autor: M Danung, D Z Egah, J A Ayeni, Gta Jombo
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Journal of Medical Laboratory Science; Vol 15, No 1 (2006)
ISSN: 1116-1043
Popis: This retrospective study was designed to ascertain the epidemiological sources and antibiotic susceptibility patterns of Proteus mirabilis strains recovered from urogenital specimens in Jos University Teaching Hospital; (JUTH) over a five year period (Janurary 2000 – December 2004). Information on epidemiological and clinical sources of P. mirabilis strains, their antibiogram profiles and the demographic data of infected subjects were obtained from the Microbiology and Records Departments. Results were analyzed by Epi Info 2002 statistical software, P values P. mirabilis were recovered from these samples; 341 (87%) were from urines, 35 (9.0%) from endocervical swabs, and 16 (4%) were from seminal fluids (P P. mirabilis strains recovered from hospital-acquired infections were more resistant than community-acquired ones to antimicrobials; Ofloxacin, ceftriaxone and amoxicillin-clavulanate were the most effective. The study has confirmed the significance of P. mirabilis involvement in hospital acquired urogenital infections and the widespread resistance of P. mirabilis strains to most antimicrobials in clinical use. This study recommends proper use of antiseptics, disinfectants and sterilization procedures in order to reduce the spread of resistant bacteria in the hospital environment.
Databáze: OpenAIRE